ID D3Z6E0_MOUSE Unreviewed; 70 AA. AC D3Z6E0; DT 20-APR-2010, integrated into UniProtKB/TrEMBL. DT 20-APR-2010, sequence version 1. DT 29-MAY-2024, entry version 70. DE SubName: Full=Transmembrane protein 106B {ECO:0000313|Ensembl:ENSMUSP00000122392.2}; DE Flags: Fragment; GN Name=Tmem106b {ECO:0000313|Ensembl:ENSMUSP00000122392.2, GN ECO:0000313|MGI:MGI:1919150}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000122392.2, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0007829|PubMed:19144319} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=19144319; DOI=10.1016/j.immuni.2008.11.006; RA Trost M., English L., Lemieux S., Courcelles M., Desjardins M., RA Thibault P.; RT "The phagosomal proteome in interferon-gamma-activated macrophages."; RL Immunity 30:143-154(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000122392.2, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000122392.2, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000122392.2} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000122392.2}; RG Ensembl; RL Submitted (FEB-2024) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR AlphaFoldDB; D3Z6E0; -. DR MaxQB; D3Z6E0; -. DR PeptideAtlas; D3Z6E0; -. DR ProteomicsDB; 369465; -. DR Antibodypedia; 43908; 144 antibodies from 29 providers. DR Ensembl; ENSMUST00000142211.8; ENSMUSP00000122392.2; ENSMUSG00000029571.15. DR AGR; MGI:1919150; -. DR MGI; MGI:1919150; Tmem106b. DR VEuPathDB; HostDB:ENSMUSG00000029571; -. DR GeneTree; ENSGT00940000158360; -. DR HOGENOM; CLU_177906_0_0_1; -. DR OMA; QTSQERY; -. DR ChiTaRS; Tmem106b; mouse. DR Proteomes; UP000000589; Chromosome 6. DR Bgee; ENSMUSG00000029571; Expressed in vestibular membrane of cochlear duct and 236 other cell types or tissues. DR ExpressionAtlas; D3Z6E0; baseline and differential. DR GO; GO:0005765; C:lysosomal membrane; IEA:TreeGrafter. DR GO; GO:0048813; P:dendrite morphogenesis; IEA:TreeGrafter. DR GO; GO:0007041; P:lysosomal transport; IEA:TreeGrafter. DR GO; GO:0032418; P:lysosome localization; IEA:TreeGrafter. DR GO; GO:0007040; P:lysosome organization; IEA:TreeGrafter. DR InterPro; IPR009790; TMEM106. DR InterPro; IPR048511; TMEM106_N. DR PANTHER; PTHR28556; TRANSMEMBRANE PROTEIN 106B; 1. DR PANTHER; PTHR28556:SF1; TRANSMEMBRANE PROTEIN 106B; 1. DR Pfam; PF21002; TMEM106_N; 1. PE 1: Evidence at protein level; KW Proteomics identification {ECO:0007829|EPD:D3Z6E0, KW ECO:0007829|MaxQB:D3Z6E0}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 2..70 FT /note="Transmembrane protein 106 N-terminal" FT /evidence="ECO:0000259|Pfam:PF21002" FT REGION 1..50 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 17..33 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 70 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000122392.2" SQ SEQUENCE 70 AA; 7589 MW; 7E6AA479121EED58 CRC64; MGKSLSHLPL HSNKEDGYDG VTSTDNMRNG LVSSEVHNED GRNGDVSQFP YVEFTGRDSV TCPTCQGTGR //