ID D3YZE6_MOUSE Unreviewed; 166 AA. AC D3YZE6; DT 20-APR-2010, integrated into UniProtKB/TrEMBL. DT 20-APR-2010, sequence version 1. DT 06-JUL-2016, entry version 44. DE RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; DE EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059}; DE Flags: Fragment; GN Name=Ugt1a6a {ECO:0000313|Ensembl:ENSMUSP00000115642, GN ECO:0000313|MGI:MGI:2137698}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000115642, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000115642, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115642, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000115642} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115642}; RG Ensembl; RL Submitted (MAY-2011) to UniProtKB. CC -!- CATALYTIC ACTIVITY: UDP-glucuronate + acceptor = UDP + acceptor CC beta-D-glucuronoside. {ECO:0000256|RuleBase:RU362059}. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362059}; CC Single-pass membrane protein {ECO:0000256|RuleBase:RU362059}. CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family. CC {ECO:0000256|RuleBase:RU003718}. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000115642}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC087780; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC087801; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR STRING; 10090.ENSMUSP00000014263; -. DR EPD; D3YZE6; -. DR MaxQB; D3YZE6; -. DR PaxDb; D3YZE6; -. DR PeptideAtlas; D3YZE6; -. DR Ensembl; ENSMUST00000140092; ENSMUSP00000115642; ENSMUSG00000054545. DR MGI; MGI:2137698; Ugt1a6a. DR eggNOG; KOG1192; Eukaryota. DR eggNOG; COG1819; LUCA. DR GeneTree; ENSGT00760000118949; -. DR HOGENOM; HOG000220831; -. DR Proteomes; UP000000589; Chromosome 1. DR Bgee; D3YZE6; -. DR ExpressionAtlas; D3YZE6; baseline. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule. DR GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC. DR GO; GO:0008152; P:metabolic process; IEA:InterPro. DR InterPro; IPR002213; UDP_glucos_trans. DR PANTHER; PTHR11926; PTHR11926; 1. DR Pfam; PF00201; UDPGT; 1. DR PROSITE; PS00375; UDPGT; 1. PE 3: Inferred from homology; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Glycosyltransferase {ECO:0000256|RuleBase:RU003718}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Transferase {ECO:0000256|RuleBase:RU003718}. FT NON_TER 166 166 {ECO:0000313|Ensembl:ENSMUSP00000115642}. SQ SEQUENCE 166 AA; 18261 MW; BF18AFA26FCFD9DA CRC64; MPNMIFLGGI NCKKKGKLTQ EFEAYVNASG EHGIVVFSLG SMVSEIPEKK AMEIAEALGR IPQTVLWRYT GTRPSNLAKN TILVKWLPQN DLLGHPKTRA FITHSGSHGI YEGICNGVPM VMMPLFGDQM DNAKRMETRG AGVTLNVLEM TADDLENALK TVINNK //