ID D3YZ96_MOUSE Unreviewed; 207 AA. AC D3YZ96; DT 20-APR-2010, integrated into UniProtKB/TrEMBL. DT 20-APR-2010, sequence version 1. DT 25-OCT-2017, entry version 48. DE RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; DE EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059}; DE Flags: Fragment; GN Name=Ugt1a7c {ECO:0000313|Ensembl:ENSMUSP00000123452, GN ECO:0000313|MGI:MGI:3032636}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000123452, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000123452, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000123452, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000123452} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000123452}; RG Ensembl; RL Submitted (MAY-2011) to UniProtKB. CC -!- CATALYTIC ACTIVITY: UDP-glucuronate + acceptor = UDP + acceptor CC beta-D-glucuronoside. {ECO:0000256|RuleBase:RU362059}. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362059}; CC Single-pass membrane protein {ECO:0000256|RuleBase:RU362059}. CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family. CC {ECO:0000256|RuleBase:RU362059, ECO:0000256|SAAS:SAAS00886888}. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000123452}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC087780; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC087801; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR SMR; D3YZ96; -. DR MaxQB; D3YZ96; -. DR PaxDb; D3YZ96; -. DR PeptideAtlas; D3YZ96; -. DR PRIDE; D3YZ96; -. DR Ensembl; ENSMUST00000150634; ENSMUSP00000123452; ENSMUSG00000090124. DR MGI; MGI:3032636; Ugt1a7c. DR eggNOG; KOG1192; Eukaryota. DR eggNOG; COG1819; LUCA. DR GeneTree; ENSGT00760000118949; -. DR HOGENOM; HOG000220832; -. DR Proteomes; UP000000589; Chromosome 1. DR Bgee; ENSMUSG00000090124; -. DR ExpressionAtlas; D3YZ96; baseline and differential. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule. DR GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC. DR GO; GO:0008152; P:metabolic process; IEA:InterPro. DR InterPro; IPR002213; UDP_glucos_trans. DR InterPro; IPR035595; UDP_glycos_trans_CS. DR PANTHER; PTHR11926; PTHR11926; 2. DR Pfam; PF00201; UDPGT; 1. DR PROSITE; PS00375; UDPGT; 1. PE 3: Inferred from homology; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Glycosyltransferase {ECO:0000256|RuleBase:RU362059}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Signal {ECO:0000256|RuleBase:RU362059}; KW Transferase {ECO:0000256|RuleBase:RU362059, KW ECO:0000256|SAAS:SAAS00886883}. FT SIGNAL 1 25 {ECO:0000256|RuleBase:RU362059}. FT CHAIN 26 207 UDP-glucuronosyltransferase. FT {ECO:0000256|RuleBase:RU362059}. FT /FTId=PRO_5005126412. FT DOMAIN 127 170 UDPGT. {ECO:0000259|PROSITE:PS00375}. FT NON_TER 207 207 {ECO:0000313|Ensembl:ENSMUSP00000123452}. SQ SEQUENCE 207 AA; 22562 MW; 7C459C3CD1AFC646 CRC64; MAPADFPASL PLCVCLLLAS GLAQAGRLLV VPMDGSHWFT MQTVVEKLLH KGHEVVVVVP EEFEAYVNAS GEHGIVVFSL GSMVSEIPEK KAMEIAEALG RIPQTVLWRY TGTRPSNLAK NTILVKWLPQ NDLLGHPKTR AFITHSGSHG IYEGICNGVP MVMMPLFGDQ MDNAKRMETR GAGVTLNVLE MTADDLENAL KTVINNK //