ID D3YZ94_MOUSE Unreviewed; 207 AA. AC D3YZ94; DT 20-APR-2010, integrated into UniProtKB/TrEMBL. DT 20-APR-2010, sequence version 1. DT 25-OCT-2017, entry version 60. DE SubName: Full=Homeobox protein OTX2 {ECO:0000313|Ensembl:ENSMUSP00000123454}; DE Flags: Fragment; GN Name=Otx2 {ECO:0000313|Ensembl:ENSMUSP00000123454, GN ECO:0000313|MGI:MGI:97451}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000123454, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000123454, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000123454, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000123454} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000123454}; RG Ensembl; RL Submitted (MAY-2011) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE- CC ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000123454}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC166574; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR SMR; D3YZ94; -. DR PaxDb; D3YZ94; -. DR PeptideAtlas; D3YZ94; -. DR Ensembl; ENSMUST00000152018; ENSMUSP00000123454; ENSMUSG00000021848. DR MGI; MGI:97451; Otx2. DR eggNOG; KOG2251; Eukaryota. DR eggNOG; ENOG4111XIJ; LUCA. DR GeneTree; ENSGT00900000140776; -. DR HOGENOM; HOG000082677; -. DR ChiTaRS; Otx2; mouse. DR Proteomes; UP000000589; Chromosome 14. DR Bgee; ENSMUSG00000021848; -. DR ExpressionAtlas; D3YZ94; baseline and differential. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0007275; P:multicellular organism development; IEA:InterPro. DR CDD; cd00086; homeodomain; 1. DR InterPro; IPR009057; Homeobox-like. DR InterPro; IPR017970; Homeobox_CS. DR InterPro; IPR001356; Homeobox_dom. DR InterPro; IPR003022; Otx2_TF. DR InterPro; IPR003025; Otx_TF. DR InterPro; IPR013851; Otx_TF_C. DR Pfam; PF00046; Homeobox; 1. DR Pfam; PF03529; TF_Otx; 1. DR PRINTS; PR01257; OTX2HOMEOBOX. DR PRINTS; PR01255; OTXHOMEOBOX. DR SMART; SM00389; HOX; 1. DR SUPFAM; SSF46689; SSF46689; 1. DR PROSITE; PS00027; HOMEOBOX_1; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108, KW ECO:0000256|RuleBase:RU000682}; KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108, KW ECO:0000256|RuleBase:RU000682}; KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, KW ECO:0000256|RuleBase:RU000682}; KW Proteomics identification {ECO:0000213|MaxQB:D3YZ94, KW ECO:0000213|PeptideAtlas:D3YZ94}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 36 96 Homeobox. {ECO:0000259|PROSITE:PS50071}. FT DNA_BIND 38 97 Homeobox. {ECO:0000256|PROSITE-ProRule: FT PRU00108}. FT NON_TER 207 207 {ECO:0000313|Ensembl:ENSMUSP00000123454}. SQ SEQUENCE 207 AA; 22742 MW; 937C55D8AD682141 CRC64; MMSYLKQPPY AVNGLSLTTS GMDLLHPSVG YPATPRKQRR ERTTFTRAQL DVLEALFAKT RYPDIFMREE VALKINLPES RVQVWFKNRR AKCRQQQQQQ QNGGQNKVRP AKKKSSPARE VSSESGTSGQ FSPPSSTSVP TIASSSAPVS IWSPASISPL SDPLSTSSSC MQRSYPMTYT QASGYSQGYA GSTSYFGGMD CGSYLTP //