ID D3YZ94_MOUSE Unreviewed; 207 AA. AC D3YZ94; DT 20-APR-2010, integrated into UniProtKB/TrEMBL. DT 20-APR-2010, sequence version 1. DT 19-FEB-2014, entry version 31. DE SubName: Full=Homeobox protein OTX2; DE Flags: Fragment; GN Name=Otx2; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] RP IDENTIFICATION. RC STRAIN=C57BL/6J; RG Ensembl; RL Submitted (MAY-2011) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC166574; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR ProteinModelPortal; D3YZ94; -. DR SMR; D3YZ94; 39-106. DR Ensembl; ENSMUST00000152018; ENSMUSP00000123454; ENSMUSG00000021848. DR MGI; MGI:97451; Otx2. DR GeneTree; ENSGT00730000110550; -. DR HOGENOM; HOG000082677; -. DR ChiTaRS; OTX2; mouse. DR NextBio; 35549737; -. DR Bgee; D3YZ94; -. DR GO; GO:0005737; C:cytoplasm; IDA:MGI. DR GO; GO:0030426; C:growth cone; IEA:Ensembl. DR GO; GO:0005634; C:nucleus; IDA:MGI. DR GO; GO:0043234; C:protein complex; IEA:Ensembl. DR GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0007411; P:axon guidance; IEA:Ensembl. DR GO; GO:0001708; P:cell fate specification; IMP:MGI. DR GO; GO:0048852; P:diencephalon morphogenesis; IGI:MGI. DR GO; GO:0009953; P:dorsal/ventral pattern formation; IMP:MGI. DR GO; GO:0007492; P:endoderm development; IGI:MGI. DR GO; GO:0042706; P:eye photoreceptor cell fate commitment; IMP:MGI. DR GO; GO:0042472; P:inner ear morphogenesis; IGI:MGI. DR GO; GO:0022037; P:metencephalon development; IGI:MGI. DR GO; GO:0030901; P:midbrain development; IMP:MGI. DR GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI. DR GO; GO:0090009; P:primitive streak formation; IMP:MGI. DR GO; GO:0006461; P:protein complex assembly; IEA:Ensembl. DR GO; GO:0032525; P:somite rostral/caudal axis specification; IMP:MGI. DR GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:GOC. DR Gene3D; 1.10.10.60; -; 1. DR InterPro; IPR017970; Homeobox_CS. DR InterPro; IPR001356; Homeobox_dom. DR InterPro; IPR009057; Homeodomain-like. DR InterPro; IPR003022; Otx2_TF. DR InterPro; IPR003025; Otx_TF. DR InterPro; IPR013851; Otx_TF_C. DR Pfam; PF00046; Homeobox; 1. DR Pfam; PF03529; TF_Otx; 1. DR PRINTS; PR01257; OTX2HOMEOBOX. DR PRINTS; PR01255; OTXHOMEOBOX. DR SMART; SM00389; HOX; 1. DR SUPFAM; SSF46689; SSF46689; 1. DR PROSITE; PS00027; HOMEOBOX_1; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. PE 3: Inferred from homology; KW Complete proteome; DNA-binding; Homeobox; Nucleus; Reference proteome. FT NON_TER 207 207 SQ SEQUENCE 207 AA; 22742 MW; 937C55D8AD682141 CRC64; MMSYLKQPPY AVNGLSLTTS GMDLLHPSVG YPATPRKQRR ERTTFTRAQL DVLEALFAKT RYPDIFMREE VALKINLPES RVQVWFKNRR AKCRQQQQQQ QNGGQNKVRP AKKKSSPARE VSSESGTSGQ FSPPSSTSVP TIASSSAPVS IWSPASISPL SDPLSTSSSC MQRSYPMTYT QASGYSQGYA GSTSYFGGMD CGSYLTP //