ID D3YXS2_MOUSE Unreviewed; 72 AA. AC D3YXS2; DT 20-APR-2010, integrated into UniProtKB/TrEMBL. DT 20-APR-2010, sequence version 1. DT 29-MAY-2024, entry version 82. DE SubName: Full=Early growth response 2 {ECO:0000313|Ensembl:ENSMUSP00000118941.2}; DE Flags: Fragment; GN Name=Egr2 {ECO:0000313|Ensembl:ENSMUSP00000118941.2, GN ECO:0000313|MGI:MGI:95296}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000118941.2, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000118941.2, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000118941.2, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000118941.2} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000118941.2}; RG Ensembl; RL Submitted (FEB-2024) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU363046}. CC -!- SIMILARITY: Belongs to the EGR C2H2-type zinc-finger protein family. CC {ECO:0000256|RuleBase:RU363046}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR AlphaFoldDB; D3YXS2; -. DR ProteomicsDB; 312771; -. DR Antibodypedia; 14464; 583 antibodies from 43 providers. DR Ensembl; ENSMUST00000146986.2; ENSMUSP00000118941.2; ENSMUSG00000037868.16. DR AGR; MGI:95296; -. DR MGI; MGI:95296; Egr2. DR VEuPathDB; HostDB:ENSMUSG00000037868; -. DR GeneTree; ENSGT00940000158394; -. DR HOGENOM; CLU_2728876_0_0_1; -. DR OMA; QCQRELH; -. DR ChiTaRS; Egr2; mouse. DR Proteomes; UP000000589; Chromosome 10. DR Bgee; ENSMUSG00000037868; Expressed in neurectoderm and 85 other cell types or tissues. DR ExpressionAtlas; D3YXS2; baseline and differential. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR InterPro; IPR021849; EGR_N. DR Pfam; PF11928; DUF3446; 1. PE 1: Evidence at protein level; KW DNA-binding {ECO:0000256|RuleBase:RU363046}; KW Metal-binding {ECO:0000256|RuleBase:RU363046}; KW Nucleus {ECO:0000256|RuleBase:RU363046}; KW Proteomics identification {ECO:0007829|EPD:D3YXS2}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Transcription {ECO:0000256|RuleBase:RU363046}; KW Transcription regulation {ECO:0000256|RuleBase:RU363046}; KW Zinc {ECO:0000256|RuleBase:RU363046}; KW Zinc-finger {ECO:0000256|RuleBase:RU363046}. FT DOMAIN 44..72 FT /note="Early growth response N-terminal" FT /evidence="ECO:0000259|Pfam:PF11928" FT NON_TER 72 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000118941.2" SQ SEQUENCE 72 AA; 7726 MW; F3507A77E7185B27 CRC64; MNGVAGDGMI NIDMTGEKRP LDLPYPSSFA PISAPRNQTF TYMGKFSIDP QYPGASCYPE GIINIVSAGI LQ //