ID D3YUT5_MOUSE Unreviewed; 139 AA. AC D3YUT5; DT 20-APR-2010, integrated into UniProtKB/TrEMBL. DT 20-APR-2010, sequence version 1. DT 27-NOV-2024, entry version 95. DE SubName: Full=Myosin VIIA {ECO:0000313|Ensembl:ENSMUSP00000114944.2}; DE Flags: Fragment; GN Name=Myo7a {ECO:0000313|Ensembl:ENSMUSP00000114944.2, GN ECO:0000313|MGI:MGI:104510}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000114944.2, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000114944.2, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000114944.2, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RG Mouse Genome Sequencing Consortium; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0007829|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and expression."; RL Cell 143:1174-1189(2010). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000114944.2} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000114944.2}; RX PubMed=21750661; RA Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., RA Chen H.C., Agarwala R., McLaren W.M., Ritchie G.R., Albracht D., RA Kremitzki M., Rock S., Kotkiewicz H., Kremitzki C., Wollam A., Trani L., RA Fulton L., Fulton R., Matthews L., Whitehead S., Chow W., Torrance J., RA Dunn M., Harden G., Threadgold G., Wood J., Collins J., Heath P., RA Griffiths G., Pelan S., Grafham D., Eichler E.E., Weinstock G., RA Mardis E.R., Wilson R.K., Howe K., Flicek P., Hubbard T.; RT "Modernizing reference genome assemblies."; RL PLoS Biol. 9:e1001091-e1001091(2011). RN [4] {ECO:0000313|Ensembl:ENSMUSP00000114944.2} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000114944.2}; RG Ensembl; RL Submitted (AUG-2024) to UniProtKB. CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR AlphaFoldDB; D3YUT5; -. DR SMR; D3YUT5; -. DR PeptideAtlas; D3YUT5; -. DR Antibodypedia; 31226; 190 antibodies from 30 providers. DR Ensembl; ENSMUST00000138627.2; ENSMUSP00000114944.2; ENSMUSG00000030761.17. DR AGR; MGI:104510; -. DR MGI; MGI:104510; Myo7a. DR VEuPathDB; HostDB:ENSMUSG00000030761; -. DR GeneTree; ENSGT00940000155350; -. DR HOGENOM; CLU_1849715_0_0_1; -. DR ChiTaRS; Myo7a; mouse. DR Proteomes; UP000000589; Chromosome 7. DR Bgee; ENSMUSG00000030761; Expressed in fourth ventricle and 173 other cell types or tissues. DR ExpressionAtlas; D3YUT5; baseline and differential. DR GO; GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW. DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro. DR Gene3D; 3.40.850.10; Kinesin motor domain; 1. DR InterPro; IPR051724; Actin_motor_Myosin. DR InterPro; IPR036961; Kinesin_motor_dom_sf. DR InterPro; IPR001609; Myosin_head_motor_dom. DR InterPro; IPR027417; P-loop_NTPase. DR PANTHER; PTHR46049; AGAP003327-PA; 1. DR PANTHER; PTHR46049:SF5; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3; 1. DR Pfam; PF00063; Myosin_head; 1. DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1. DR PROSITE; PS51456; MYOSIN_MOTOR; 1. PE 1: Evidence at protein level; KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782}; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840}; KW Motor protein {ECO:0000256|ARBA:ARBA00023175}; KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE- KW ProRule:PRU00782}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840}; KW Proteomics identification {ECO:0007829|PeptideAtlas:D3YUT5, KW ECO:0007829|ProteomicsDB:D3YUT5}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 65..139 FT /note="Myosin motor" FT /evidence="ECO:0000259|PROSITE:PS51456" FT NON_TER 139 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000114944.2" SQ SEQUENCE 139 AA; 15756 MW; 4E912E4C58B796CF CRC64; MVILQKGDYV WMDLKSGQEF DVPIGAVVKL CDSGQIQVVD DEDNEHWISP QNATHIKPMH PTSVHGVEDM IRLGDLNEAG ILRNLLIRYR DHLIYTSCGG RTYTGSILVA VNPYQLLSIY SPEHIRQYTN KKIGEMPPH //