ID D3YTP0_MOUSE Unreviewed; 418 AA. AC D3YTP0; DT 20-APR-2010, integrated into UniProtKB/TrEMBL. DT 05-OCT-2016, sequence version 8. DT 12-SEP-2018, entry version 63. DE SubName: Full=Metalloreductase STEAP3 {ECO:0000313|Ensembl:ENSMUSP00000121046}; DE Flags: Fragment; GN Name=Steap3 {ECO:0000313|Ensembl:ENSMUSP00000121046, GN ECO:0000313|MGI:MGI:1915678}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000121046, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000213|PubMed:17242355} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=17242355; DOI=10.1073/pnas.0609836104; RA Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.; RT "Large-scale phosphorylation analysis of mouse liver."; RL Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). RN [2] {ECO:0000213|PubMed:19144319} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=19144319; DOI=10.1016/j.immuni.2008.11.006; RA Trost M., English L., Lemieux S., Courcelles M., Desjardins M., RA Thibault P.; RT "The phagosomal proteome in interferon-gamma-activated macrophages."; RL Immunity 30:143-154(2009). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000121046, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000121046, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [4] {ECO:0000213|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and RT expression."; RL Cell 143:1174-1189(2010). RN [5] {ECO:0000313|Ensembl:ENSMUSP00000121046} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000121046}; RG Ensembl; RL Submitted (MAY-2011) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC084310; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC139867; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR SMR; D3YTP0; -. DR PeptideAtlas; D3YTP0; -. DR PRIDE; D3YTP0; -. DR Ensembl; ENSMUST00000140490; ENSMUSP00000121046; ENSMUSG00000026389. DR MGI; MGI:1915678; Steap3. DR eggNOG; ENOG410IF4F; Eukaryota. DR eggNOG; COG2085; LUCA. DR GeneTree; ENSGT00390000008042; -. DR HOGENOM; HOG000234491; -. DR Reactome; R-MMU-6803204; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release. DR Reactome; R-MMU-917977; Transferrin endocytosis and recycling. DR Proteomes; UP000000589; Chromosome 1. DR Bgee; ENSMUSG00000026389; Expressed in 175 organ(s), highest expression level in left lobe of liver. DR ExpressionAtlas; D3YTP0; baseline and differential. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR InterPro; IPR013130; Fe3_Rdtase_TM_dom. DR InterPro; IPR036291; NAD(P)-bd_dom_sf. DR InterPro; IPR028939; P5C_Rdtase_cat_N. DR Pfam; PF03807; F420_oxidored; 1. DR Pfam; PF01794; Ferric_reduct; 1. DR SUPFAM; SSF51735; SSF51735; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Proteomics identification {ECO:0000213|EPD:D3YTP0, KW ECO:0000213|MaxQB:D3YTP0, ECO:0000213|PeptideAtlas:D3YTP0}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 214 232 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 252 280 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 305 326 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 359 379 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 391 412 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 30 117 F420_oxidored. {ECO:0000259|Pfam: FT PF03807}. FT DOMAIN 260 404 Ferric oxidoreductase. {ECO:0000259|Pfam: FT PF01794}. FT NON_TER 418 418 {ECO:0000313|Ensembl:ENSMUSP00000121046}. SQ SEQUENCE 418 AA; 46879 MW; B2905771733A9A96 CRC64; MSGEMDKPLI SRRLVDSDGS LAEVPKEAPK VGILGSGDFA RSLATRLVGS GFSVVVGSRN PKRTAGLFPS LAQVTFQEEA VSSPEVIFVA VFREHYSSLC SLADQLAGKI LVDVSNPTEK EHLQHRQSNA EYLASLFPAC TVVKAFNVIS AWALQAGPRD GNRQVLICSD QPEAKRTISE MARAMGFTPL DMGSLASARE VEAIPLRLLP SWKVPTLLAL GLFVCFYTYN FIRDVLQPYI RKDENKFYKM PLSVVNTTLP CVAYVLLSLV YLPGVLAAAL QLRRGTKYQR FPDWLDHWLQ HRKQIGLLSF FFAMLHALYS FCLPLRRSHR YDLVNLAVKQ VLANKSRLWA EEEVWRMEIY LSLGVLALGM LSLLAVTSLP SIANSLNWKE FSFVQQVFYL LRILSSPLYS FYTNLSKL //