ID D3YTP0_MOUSE Unreviewed; 418 AA. AC D3YTP0; DT 20-APR-2010, integrated into UniProtKB/TrEMBL. DT 04-FEB-2015, sequence version 4. DT 04-FEB-2015, entry version 41. DE SubName: Full=Metalloreductase STEAP3 {ECO:0000313|Ensembl:ENSMUSP00000121046}; DE Flags: Fragment; GN Name=Steap3 {ECO:0000313|Ensembl:ENSMUSP00000121046, GN ECO:0000313|MGI:MGI:1915678}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000121046, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000213|PubMed:17242355} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=17242355; DOI=10.1073/pnas.0609836104; RA Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.; RT "Large-scale phosphorylation analysis of mouse liver."; RL Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). RN [2] {ECO:0000213|PubMed:19144319} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=19144319; DOI=10.1016/j.immuni.2008.11.006; RA Trost M., English L., Lemieux S., Courcelles M., Desjardins M., RA Thibault P.; RT "The phagosomal proteome in interferon-gamma-activated macrophages."; RL Immunity 30:143-154(2009). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000121046, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000121046, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [4] {ECO:0000313|Ensembl:ENSMUSP00000121046} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000121046}; RG Ensembl; RL Submitted (MAY-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000121046}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC084310; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC139867; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR PRIDE; D3YTP0; -. DR Ensembl; ENSMUST00000140490; ENSMUSP00000121046; ENSMUSG00000026389. DR MGI; MGI:1915678; Steap3. DR GeneTree; ENSGT00390000008042; -. DR HOGENOM; HOG000234491; -. DR OrthoDB; EOG7Z0JWH; -. DR NextBio; 35548436; -. DR Proteomes; UP000000589; Chromosome 1. DR Bgee; D3YTP0; -. DR ExpressionAtlas; D3YTP0; baseline and differential. DR GO; GO:0005768; C:endosome; IDA:MGI. DR GO; GO:0005771; C:multivesicular body; ISA:MGI. DR GO; GO:0005886; C:plasma membrane; IDA:MGI. DR GO; GO:0008823; F:cupric reductase activity; IDA:MGI. DR GO; GO:0052851; F:ferric-chelate reductase (NADPH) activity; IDA:MGI. DR GO; GO:0000293; F:ferric-chelate reductase activity; IDA:MGI. DR GO; GO:0015677; P:copper ion import; IDA:MGI. DR GO; GO:1990182; P:exosomal secretion; IMP:MGI. DR GO; GO:0097461; P:ferric iron import into cell; IDA:MGI. DR GO; GO:0006826; P:iron ion transport; IMP:MGI. DR GO; GO:0055114; P:oxidation-reduction process; IDA:MGI. DR GO; GO:1902167; P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IMP:MGI. DR GO; GO:0009306; P:protein secretion; ISA:MGI. DR Gene3D; 3.40.50.720; -; 1. DR InterPro; IPR013130; Fe3_Rdtase_TM_dom. DR InterPro; IPR016040; NAD(P)-bd_dom. DR InterPro; IPR028939; ProC_N. DR Pfam; PF03807; F420_oxidored; 1. DR Pfam; PF01794; Ferric_reduct; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT NON_TER 418 418 {ECO:0000313|Ensembl:ENSMUSP00000121046}. SQ SEQUENCE 418 AA; 46879 MW; B2905771733A9A96 CRC64; MSGEMDKPLI SRRLVDSDGS LAEVPKEAPK VGILGSGDFA RSLATRLVGS GFSVVVGSRN PKRTAGLFPS LAQVTFQEEA VSSPEVIFVA VFREHYSSLC SLADQLAGKI LVDVSNPTEK EHLQHRQSNA EYLASLFPAC TVVKAFNVIS AWALQAGPRD GNRQVLICSD QPEAKRTISE MARAMGFTPL DMGSLASARE VEAIPLRLLP SWKVPTLLAL GLFVCFYTYN FIRDVLQPYI RKDENKFYKM PLSVVNTTLP CVAYVLLSLV YLPGVLAAAL QLRRGTKYQR FPDWLDHWLQ HRKQIGLLSF FFAMLHALYS FCLPLRRSHR YDLVNLAVKQ VLANKSRLWA EEEVWRMEIY LSLGVLALGM LSLLAVTSLP SIANSLNWKE FSFVQQVFYL LRILSSPLYS FYTNLSKL //