ID D3Y2F8_MOUSE Unreviewed; 644 AA. AC D3Y2F8; DT 20-APR-2010, integrated into UniProtKB/TrEMBL. DT 20-APR-2010, sequence version 1. DT 12-OCT-2022, entry version 56. DE SubName: Full=Cyclin-like protein 4 {ECO:0000313|EMBL:ADC80900.1}; GN Name=Cnnm4 {ECO:0000313|MGI:MGI:2151060}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:ADC80900.1}; RN [1] {ECO:0000313|EMBL:ADC80900.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Swiss Albino {ECO:0000313|EMBL:ADC80900.1}; RC TISSUE=Testis {ECO:0000313|EMBL:ADC80900.1}; RA Prasad V.S., Kumar P.G.; RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. CC -!- SIMILARITY: Belongs to the ACDP family. CC {ECO:0000256|ARBA:ARBA00010484}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GU390541; ADC80900.1; -; mRNA. DR PeptideAtlas; D3Y2F8; -. DR MGI; MGI:2151060; Cnnm4. DR ChiTaRS; Cnnm4; mouse. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW. DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro. DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1. DR Gene3D; 2.60.120.10; -; 1. DR Gene3D; 3.10.580.10; -; 1. DR InterPro; IPR045095; ACDP. DR InterPro; IPR000644; CBS_dom. DR InterPro; IPR046342; CBS_dom_sf. DR InterPro; IPR018490; cNMP-bd_dom_sf. DR InterPro; IPR002550; CNNM. DR InterPro; IPR044751; Ion_transp-like_CBS. DR InterPro; IPR014710; RmlC-like_jellyroll. DR PANTHER; PTHR12064; PTHR12064; 1. DR Pfam; PF00571; CBS; 1. DR Pfam; PF01595; DUF21; 1. DR SUPFAM; SSF51206; SSF51206; 1. DR SUPFAM; SSF54631; SSF54631; 1. DR PROSITE; PS51371; CBS; 1. DR PROSITE; PS51846; CNNM; 1. PE 2: Evidence at transcript level; KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703}; KW Cell membrane {ECO:0000256|ARBA:ARBA00022475}; KW Ion transport {ECO:0000256|ARBA:ARBA00023065}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE- KW ProRule:PRU01193}; Repeat {ECO:0000256|ARBA:ARBA00022737}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE- KW ProRule:PRU01193}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE- KW ProRule:PRU01193}; Transport {ECO:0000256|ARBA:ARBA00023065}. FT TRANSMEM 52..76 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 110..131 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 137..156 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 168..188 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 48..228 FT /note="CNNM transmembrane" FT /evidence="ECO:0000259|PROSITE:PS51846" FT DOMAIN 315..381 FT /note="CBS" FT /evidence="ECO:0000259|PROSITE:PS51371" SQ SEQUENCE 644 AA; 73252 MW; 8B8F9E6431CA979B CRC64; MLVVITKFLR RSENTKLYAL CTRPRADGPW TRWTDKDSLL FMVEEHGRFL PLWLHILLVM VLLVLSGIFS GLNLGLMALD PMELRIVQSC GTEKERKYAR KIEPIRRKGN YLLCSLLLGN VLVNTSLTIL LDNLIGSGIM AVASSTIGIV IFGEILPQAL CSRHGLAVGA NTIVLTKVFM LLTFPLSFPI SKLLDFVLGQ EIRTVYNREK LMEMLKVTEP YNDLVKEELN MIQGALELRT KTVEDIMTQL HDCFMIRSDA ILDFNTMSEI MESGYTRIPV FEDEQSNIVD ILYVKDLAFV DPDDCTPLKT ITRFYNHPVH FVFHDTKLDA MLEEFKKGKS HLAIVQKVNN EGEGDPFYEV LGLVTLEDVI EEIIKSEILD ESDMYIDNRT LKRVSVKNKR DFSAFKDTDN ELKVKISPQL LLAAHRFLAT EVPQFSPSLM SEKILLRLLK YPDVIQELRF NEHNRYCVRH YLYTRNKPAD CFVLILQGKV EVEAGKENMK FETGAFSYYG TMALSVAPPD RSPALPTPLS RSASLSYPDR NTDLTSTSLA GSNQFGRCIL GQYVSDFSVR ALTDLQYIKI TRQQYQNGLM ASRIDNSPQP TFDGCATCSE NFMERPELPP VDETTTLLNE RNSLLHRASE EETI //