ID D3DM41_YEAST Unreviewed; 451 AA. AC D3DM41; DT 23-MAR-2010, integrated into UniProtKB/TrEMBL. DT 23-MAR-2010, sequence version 1. DT 10-AUG-2010, entry version 5. DE SubName: Full=GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4/Ypt/rab family of GTP binding proteins; GN Name=GDI1; ORFNames=YER136W; OS Saccharomyces cerevisiae S288c. OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomyceta; OC Saccharomycotina; Saccharomycetes; Saccharomycetales; OC Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=559292; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=S288c; RX MEDLINE=97002444; PubMed=8849441; DOI=10.1126/science.274.5287.546; RA Goffeau A., Barrell B.G., Bussey H., Davis R.W., Dujon B., RA Feldmann H., Galibert F., Hoheisel J.D., Jacq C., Johnston M., RA Louis E.J., Mewes H.W., Murakami Y., Philippsen P., Tettelin H., RA Oliver S.G.; RT "Life with 6000 genes."; RL Science 274:546-546(1996). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=S288c; RX MEDLINE=97313264; PubMed=9169868; RA Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., RA Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., RA Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., RA Hunicke-Smith S., Hyman R.W., Kayser A., Komp C., Lashkari D., Lew H., RA Lin D., Mosedale D., Nakahara K., Namath A., Norgren R., Oefner P., RA Oh C., Petel F.X., Roberts D., Sehl P., Schramm S., Shogren T., RA Smith V., Taylor P., Wei Y., Botstein D., Davis R.W.; RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome V."; RL Nature 387:78-81(1997). RN [3] RP NUCLEOTIDE SEQUENCE. RC STRAIN=S288c; RG Saccharomyces Genome Database; RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases. CC -!- MISCELLANEOUS: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ third party annotation (TPA) entry. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BK006939; DAA07795.1; -; Genomic_DNA. DR ProteinModelPortal; D3DM41; -. DR GenomeReviews; U00092_GR; YER136W. DR GO; GO:0005624; C:membrane fraction; IDA:SGD. DR GO; GO:0005625; C:soluble fraction; IDA:SGD. DR GO; GO:0005093; F:Rab GDP-dissociation inhibitor activity; IDA:SGD. DR GO; GO:0015031; P:protein transport; IEA:InterPro. DR GO; GO:0043087; P:regulation of GTPase activity; IEA:InterPro. DR GO; GO:0016192; P:vesicle-mediated transport; IMP:SGD. DR InterPro; IPR018203; GDP_dissociation_inhibitor. DR InterPro; IPR002005; Rab_GDI_REP. DR InterPro; IPR000806; RabGDI. DR PANTHER; PTHR11787; Rab_GDI_REP; 1. DR Pfam; PF00996; GDI; 1. DR PRINTS; PR00892; RABGDI. DR PRINTS; PR00891; RABGDIREP. PE 4: Predicted; SQ SEQUENCE 451 AA; 51206 MW; 48CF8D45FC031772 CRC64; MDQETIDTDY DVIVLGTGIT ECILSGLLSV DGKKVLHIDK QDHYGGEAAS VTLSQLYEKF KQNPISKEER ESKFGKDRDW NVDLIPKFLM ANGELTNILI HTDVTRYVDF KQVSGSYVFK QGKIYKVPAN EIEAISSPLM GIFEKRRMKK FLEWISSYKE DDLSTHQGLD LDKNTMDEVY YKFGLGNSTK EFIGHAMALW TNDDYLQQPA RPSFERILLY CQSVARYGKS PYLYPMYGLG ELPQGFARLS AIYGGTYMLD TPIDEVLYKK DTGKFEGVKT KLGTFKAPLV IADPTYFPEK CKSTGQRVIR AICILNHPVP NTSNADSLQI IIPQSQLGRK SDIYVAIVSD AHNVCSKGHY LAIISTIIET DKPHIELEPA FKLLGPIEEK FMGIAELFEP REDGSKDNIY LSRSYDASSH FESMTDDVKD IYFRVTGHPL VLKQRQEQEK Q //