ID   D2Y611_HUMAN            Unreviewed;       380 AA.
AC   D2Y611;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   22-JAN-2014, entry version 27.
DE   RecName: Full=Cytochrome b;
GN   Name=CYTB;
OS   Homo sapiens (Human).
OG   Mitochondrion.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RA   Greenspan B.;
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RA   Greenspan B.;
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RA   Greenspan B.;
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=22482806; DOI=10.1016/j.ajhg.2012.03.002;
RA   Behar D.M., van Oven M., Rosset S., Metspalu M., Loogvali E.L.,
RA   Silva N.M., Kivisild T., Torroni A., Villems R.;
RT   "A "Copernican" reassessment of the human mitochondrial DNA tree from
RT   its root.";
RL   Am. J. Hum. Genet. 90:675-684(2012).
RN   [5]
RP   NUCLEOTIDE SEQUENCE.
RA   Greenspan B.;
RL   Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
RN   [6]
RP   NUCLEOTIDE SEQUENCE.
RA   Ciccozzi M., Montieri S., Farchi F., Beshkov D., Rezza G.;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [7]
RP   NUCLEOTIDE SEQUENCE.
RA   Nishi O., Iiyama K., Yasunaga-Aoki C., Shimizu S.;
RT   "The phylogenetic status and pathogenicity of a new isolate of
RT   Metarhizium sp. from a fruit beetle larvae in Japan.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
RN   [8]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=24104924; DOI=10.1038/ncomms3543;
RA   Costa M.D., Pereira J.B., Pala M., Fernandes V., Olivieri A.,
RA   Achilli A., Perego U.A., Rychkov S., Naumova O., Hatina J.,
RA   Woodward S.R., Eng K.K., Macaulay V., Carr M., Soares P., Pereira L.,
RA   Richards M.B.;
RT   "A substantial prehistoric European ancestry amongst Ashkenazi
RT   maternal lineages.";
RL   Nat. Commun. 4:2543-2543(2013).
RN   [9]
RP   NUCLEOTIDE SEQUENCE.
RA   Greenspan B.;
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the ubiquinol-cytochrome c reductase
CC       complex (complex III or cytochrome b-c1 complex), which is a
CC       respiratory chain that generates an electrochemical potential
CC       coupled to ATP synthesis (By similarity).
CC   -!- COFACTOR: Binds 2 heme groups non-covalently (By similarity).
CC   -!- SIMILARITY: Belongs to the cytochrome b family.
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DR   EMBL; EU239477; ABW76523.2; -; Genomic_DNA.
DR   EMBL; GU361772; ADB07260.1; -; Genomic_DNA.
DR   EMBL; GU797785; ADC79269.1; -; Genomic_DNA.
DR   EMBL; JQ702168; AFF66154.1; -; Genomic_DNA.
DR   EMBL; JQ702304; AFF67922.1; -; Genomic_DNA.
DR   EMBL; JQ702745; AFF73655.1; -; Genomic_DNA.
DR   EMBL; JQ702752; AFF73746.1; -; Genomic_DNA.
DR   EMBL; JQ702919; AFF75917.1; -; Genomic_DNA.
DR   EMBL; JQ703008; AFF77074.1; -; Genomic_DNA.
DR   EMBL; JQ703130; AFF78660.1; -; Genomic_DNA.
DR   EMBL; JQ704057; AFF90711.1; -; Genomic_DNA.
DR   EMBL; JQ705400; AFG08170.1; -; Genomic_DNA.
DR   EMBL; JQ705685; AFG11875.1; -; Genomic_DNA.
DR   EMBL; JQ705686; AFG11888.1; -; Genomic_DNA.
DR   EMBL; JX091694; AFK31707.1; -; Genomic_DNA.
DR   EMBL; JX273283; AFP91726.1; -; Genomic_DNA.
DR   EMBL; JX891380; AFU76054.1; -; Genomic_DNA.
DR   EMBL; KC158584; AFY07375.1; -; Genomic_DNA.
DR   EMBL; KF048032; AGL96430.1; -; Genomic_DNA.
DR   NextBio; 35489725; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR   GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0022904; P:respiratory electron transport chain; IEA:InterPro.
DR   Gene3D; 1.20.810.10; -; 1.
DR   InterPro; IPR016175; Cyt_b/b6.
DR   InterPro; IPR005798; Cyt_b/b6_C.
DR   InterPro; IPR005797; Cyt_b/b6_N.
DR   InterPro; IPR027387; Cytb/b6-like.
DR   InterPro; IPR016174; Di-haem_cyt_TM.
DR   PANTHER; PTHR19271:SF0; PTHR19271:SF0; 1.
DR   Pfam; PF00032; Cytochrom_B_C; 1.
DR   Pfam; PF13631; Cytochrom_B_N_2; 1.
DR   SUPFAM; SSF81342; SSF81342; 1.
DR   SUPFAM; SSF81648; SSF81648; 1.
DR   PROSITE; PS51003; CYTB_CTER; 1.
DR   PROSITE; PS51002; CYTB_NTER; 1.
PE   3: Inferred from homology;
KW   Electron transport; Heme; Iron; Membrane; Metal-binding;
KW   Mitochondrion; Respiratory chain; Transmembrane; Transport.
SQ   SEQUENCE   380 AA;  42665 MW;  845269B40DDEC106 CRC64;
     MTPMRKINPL MKLINHSLID LPTPSNISAW WNFGSLLGAC LILQITTGLF LAMHYSPDAS
     TAFSSIAHIT RDVNYGWIIR YLHANGASMF FICLFLHIGR GLYYGSFLYS ETWNIGIILL
     LATMATAFMG YVLPWGQMSF WGATVITNLL SAIPYIGTDL VQWIWGGYSV NSPTLTRFFT
     FHFILPFIIA ALAALHLLFL HETGSNNPLG ITSHSDKITF HPYYTIKDAL GLLLFLLSLM
     TLTLFSPDLL GDPDNYTLAN PLNTPPHIKP EWYFLFAYTI LRSVPNKLGG VLALLLSILI
     LAMIPILHMS KQQSMMFRPL SQSLYWLLAA DLLILTWIGG QPVSYPFTII GQVASVLYFT
     TILILMPTIS LIENKMLKWA
//