ID D2KKE9_CLOBO Unreviewed; 1163 AA. AC D2KKE9; DT 09-FEB-2010, integrated into UniProtKB/TrEMBL. DT 09-FEB-2010, sequence version 1. DT 20-JUN-2018, entry version 31. DE SubName: Full=Nontoxic-nonhemagglutinin {ECO:0000313|EMBL:ADA79541.1}; OS Clostridium botulinum. OC Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; OC Clostridium. OX NCBI_TaxID=1491 {ECO:0000313|EMBL:ADA79541.1}; RN [1] {ECO:0000313|EMBL:ADA79541.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=CDC 54085 {ECO:0000313|EMBL:ADA79541.1}, CDC 54090 RC {ECO:0000313|EMBL:ADA79544.1}, and CDC 54096 RC {ECO:0000313|EMBL:ADA79543.1}; RX PubMed=20511432; DOI=10.1128/AEM.03109-09; RA Raphael B.H., Choudoir M.J., Luquez C., Fernandez R., Maslanka S.E.; RT "Sequence diversity of genes encoding botulinum neurotoxin type F."; RL Appl. Environ. Microbiol. 76:4805-4812(2010). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GU221929; ADA79541.1; -; Genomic_DNA. DR EMBL; GU299675; ADA79543.1; -; Genomic_DNA. DR EMBL; GU299676; ADA79544.1; -; Genomic_DNA. DR RefSeq; WP_025775292.1; NZ_MWIY01000007.1. DR GO; GO:0005576; C:extracellular region; IEA:InterPro. DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0046929; P:negative regulation of neurotransmitter secretion; IEA:InterPro. DR GO; GO:0009405; P:pathogenesis; IEA:InterPro. DR Gene3D; 1.20.1120.10; -; 1. DR InterPro; IPR000395; Bot/tetX_LC. DR InterPro; IPR036248; Clostridium_toxin_transloc. DR InterPro; IPR013320; ConA-like_dom_sf. DR InterPro; IPR013677; Nontoxic_nonhemagglutn_C. DR InterPro; IPR012928; Toxin_rcpt-bd_N. DR Pfam; PF08470; NTNH_C; 1. DR Pfam; PF01742; Peptidase_M27; 1. DR Pfam; PF07953; Toxin_R_bind_N; 1. DR PRINTS; PR00760; BONTOXILYSIN. DR SUPFAM; SSF49899; SSF49899; 1. DR SUPFAM; SSF58091; SSF58091; 1. PE 4: Predicted; FT DOMAIN 1 364 Peptidase_M27. {ECO:0000259|Pfam: FT PF01742}. FT DOMAIN 814 988 Toxin_R_bind_N. {ECO:0000259|Pfam: FT PF07953}. FT DOMAIN 998 1161 NTNH_C. {ECO:0000259|Pfam:PF08470}. SQ SEQUENCE 1163 AA; 135043 MW; FA86AFD65F2ACC06 CRC64; MKINNNFNID SPVDNKDVAI VRGRKTDTFF KVFQVAPNIW VAPERYYGES LNINEDQKSD GGIYDSNFLL TNDEKDEFLE ATVKILQRIN NNVVGAKLLS LISTAIPFPY EYKPGDYRQT NYLVSKDNQH YYTANLVIFG PGTNIVENNA VYYKKEDSEN GMGTISEIWF QPFLTYKYDQ FYVDPALELI KCLIKSLYYL YGIKPSDDLS IPCRLRSEFN SLEYSELDMV DFLISGGTEY KLLDTNPYWF TDNYFIDAPK NFEKYKNDYE TKIKNNNDIA NSIKLYLEQK FKINAQDIWE LNLSYFSTEF EIMMPEIFNN ALNHYYRKEY YVIDYFKNYN INGFINGQIK TILPLSKYNK NITNKPELVV NLINENNTVL MKSNVYGDGL KGTMDNFYAA YKIPYNIGDE YHINYSYLNN VNVEEINNIP PINDADIYPY RKNSDPFIPV YNITETKEIN TTTPFSVNYL QAQVTNSNDI SLSSDFSKVV SSKDRSLVYS FLDNTIDYLD SIKYDGPIDT DKKYYLWLKE IFRNYSFDMT ETQEVNTPCG INKVVPWLGK ALNILNTGNS FIEEFKSLGP ISLINKKENI TMPKIGIDEI PNSMLNLSFK DLSENLFNIF FKNNSYFEKI YYDFLDQWWT QYYSQYFDLI CMAKRSVLAQ ESLIKKIIQK KLSYLIGNAN ISSDNLALMN LTTTNTLRDI SNESQIAMNN VDSFLNDAAI CVFESNIYPK FISFMEQCIN NINKDTKEFI QKCINITENE KLQLISQNTF SSLDFDFLNI ENLKSLFSSE TALLIKEETS PYELVLYAFQ ELSNNVIGDA SGKNTSIEYS KDIGLVYGIN SDALYLNGSN QSISFSNDFF ENGLTNSFSI YFWLRNLGQD TTKSKLIGSK EDNCGWEIYF QDTGLVFNMI DSNGDEKNIY LSDVSNNSWH YITISVDRLK EQLLIFIDDN LVVNESIKEI LNIYSSNIIS LLSDNNASYI EGLTILNKPT TGEEVLSNYF KNLNNSYIRD SNEERLEYNK TYQLYNYVFS DKPICEVKQN NNIYLTINNT NNLNLQASKF KLLSINPNKQ YVQKFDEVII SILDNMEKYI DISEDNRLQL IDNKNSAKKM LISNDIFISN CLTLSYNGKY ICLSMKDENY NWMICNNESN IPKRAYLWIL KEV //