ID D2K4B4_9TELE Unreviewed; 273 AA. AC D2K4B4; DT 09-FEB-2010, integrated into UniProtKB/TrEMBL. DT 09-FEB-2010, sequence version 1. DT 14-DEC-2022, entry version 41. DE RecName: Full=Rhodopsin {ECO:0000256|RuleBase:RU004951}; DE Flags: Fragment; GN Name=RH {ECO:0000313|EMBL:ACZ64913.1}; OS Micropoecilia picta (swamp guppy). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; OC Micropoecilia. OX NCBI_TaxID=69234 {ECO:0000313|EMBL:ACZ64913.1}; RN [1] {ECO:0000313|EMBL:ACZ64913.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=19922806; DOI=10.1016/j.ympev.2009.11.006; RA Meredith R.W., Pires M.N., Reznick D.N., Springer M.S.; RT "Molecular phylogenetic relationships and the evolution of the placenta in RT Poecilia (Micropoecilia) (Poeciliidae: Cyprinodontiformes)."; RL Mol. Phylogenet. Evol. 55:631-639(2010). CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141, CC ECO:0000256|RuleBase:RU004951}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004951}. CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family. Opsin CC subfamily. {ECO:0000256|RuleBase:RU004951}. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of CC feature annotation. {ECO:0000256|RuleBase:RU004951}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GU179279; ACZ64913.1; -; Genomic_DNA. DR EMBL; GU179280; ACZ64914.1; -; Genomic_DNA. DR AlphaFoldDB; D2K4B4; -. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell. DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW. DR GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW. DR GO; GO:0007602; P:phototransduction; IEA:UniProtKB-KW. DR GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW. DR InterPro; IPR000276; GPCR_Rhodpsn. DR InterPro; IPR017452; GPCR_Rhodpsn_7TM. DR InterPro; IPR001760; Opsin. DR InterPro; IPR000732; Rhodopsin. DR Pfam; PF00001; 7tm_1; 1. DR PRINTS; PR00237; GPCRRHODOPSN. DR PRINTS; PR00238; OPSIN. DR PRINTS; PR00579; RHODOPSIN. DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1. DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1. PE 3: Inferred from homology; KW Chromophore {ECO:0000256|RuleBase:RU004951}; KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157}; KW G-protein coupled receptor {ECO:0000256|RuleBase:RU004951}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004951}; KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}; KW Photoreceptor protein {ECO:0000256|RuleBase:RU004951}; KW Receptor {ECO:0000256|RuleBase:RU004951}; KW Retinal protein {ECO:0000256|RuleBase:RU004951}; KW Sensory transduction {ECO:0000256|RuleBase:RU004951}; KW Transducer {ECO:0000256|RuleBase:RU004951}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, KW ECO:0000256|RuleBase:RU004951}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|RuleBase:RU004951}; Vision {ECO:0000256|ARBA:ARBA00023305}. FT TRANSMEM 12..32 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004951" FT TRANSMEM 44..64 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004951" FT TRANSMEM 84..102 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004951" FT TRANSMEM 123..142 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004951" FT TRANSMEM 172..192 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004951" FT TRANSMEM 223..245 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU004951" FT DOMAIN 23..273 FT /note="G_PROTEIN_RECEP_F1_2" FT /evidence="ECO:0000259|PROSITE:PS50262" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:ACZ64913.1" FT NON_TER 273 FT /evidence="ECO:0000313|EMBL:ACZ64913.1" SQ SEQUENCE 273 AA; 30747 MW; ACF72B31BA7E4F68 CRC64; VSPAAYACLG AYMFFLILVG FPINFLTLYV TIEHKKLRTP LNYILLNLAV ADLFMVFGGF TTTIYTSMHG YFVLGRLGCN LEGYFATLGG EIGLWSLVVL AVERWLVVCK PISNFRFSEN HAIMGLVFTW IMANTCAAPP LLGWSRYIPE GMQCSCGVDY YTRAEGFNNE SFVVYMFICH FCIPLVVVFF CYGRLLCAVK EAAAAQQESE TTQRAEREVT RMVVIMVIGF LVCWIPYASV AWYIFTHQGS EFGPLFMTIP AFFAKTASIY NPM //