ID D2ABY8_SHIF2 Unreviewed; 448 AA. AC D2ABY8; DT 09-FEB-2010, integrated into UniProtKB/TrEMBL. DT 09-FEB-2010, sequence version 1. DT 24-JAN-2024, entry version 59. DE SubName: Full=IS4 ORF {ECO:0000313|EMBL:ADA76192.1}; GN OrderedLocusNames=SFxv_4241 {ECO:0000313|EMBL:ADA76192.1}; OS Shigella flexneri serotype X (strain 2002017). OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Shigella. OX NCBI_TaxID=591020 {ECO:0000313|EMBL:ADA76192.1, ECO:0000313|Proteomes:UP000001884}; RN [1] {ECO:0000313|EMBL:ADA76192.1, ECO:0000313|Proteomes:UP000001884} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=2002017 {ECO:0000313|EMBL:ADA76192.1, RC ECO:0000313|Proteomes:UP000001884}; RX PubMed=19955273; DOI=10.1128/JCM.00614-09; RA Ye C., Lan R., Xia S., Zhang J., Sun Q., Zhang S., Jing H., Wang L., Li Z., RA Zhou Z., Zhao A., Cui Z., Cao J., Jin D., Huang L., Wang Y., Luo X., RA Bai X., Wang Y., Wang P., Xu Q., Xu J.; RT "Emergence of a new multidrug-resistant serotype X variant in an epidemic RT clone of Shigella flexneri."; RL J. Clin. Microbiol. 48:419-426(2010). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP001383; ADA76192.1; -; Genomic_DNA. DR RefSeq; WP_005082871.1; NC_017328.1. DR AlphaFoldDB; D2ABY8; -. DR KEGG; sfe:SFxv_4241; -. DR PATRIC; fig|591020.3.peg.4548; -. DR HOGENOM; CLU_028400_1_1_6; -. DR OMA; MAVKELW; -. DR Proteomes; UP000001884; Chromosome. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0004803; F:transposase activity; IEA:InterPro. DR GO; GO:0006313; P:DNA transposition; IEA:InterPro. DR InterPro; IPR012337; RNaseH-like_sf. DR InterPro; IPR047952; Transpos_IS4. DR InterPro; IPR002559; Transposase_11. DR InterPro; IPR024473; Transposases_IS4_N. DR NCBIfam; NF033592; transpos_IS4_1; 1. DR PANTHER; PTHR37529; TRANSPOSASE INSG FOR INSERTION SEQUENCE ELEMENT IS4-RELATED; 1. DR PANTHER; PTHR37529:SF1; TRANSPOSASE INSG FOR INSERTION SEQUENCE ELEMENT IS4-RELATED; 1. DR Pfam; PF01609; DDE_Tnp_1; 1. DR Pfam; PF13006; Nterm_IS4; 1. DR SUPFAM; SSF53098; Ribonuclease H-like; 1. PE 4: Predicted; FT DOMAIN 24..115 FT /note="Transposase IS4 N-terminal" FT /evidence="ECO:0000259|Pfam:PF13006" FT DOMAIN 132..358 FT /note="Transposase IS4-like" FT /evidence="ECO:0000259|Pfam:PF01609" SQ SEQUENCE 448 AA; 50987 MW; 6B650E9F11B011FB CRC64; MFPDFFMHIG QALDLVSRYD SLRNPLTSLG DYLDPELISR CLAESGTVTL RKRRLPLEMM VWCIVGMALE RKEPLHQIVN RLDIMLPGNR PFVAPSAVIQ ARQRLGSEAV RRVFTKTAQL WHNATPHPHW CGLTLLAIDG VFWRTPDTPE NDAAFPRQTH AGNPALYPQV KMVCQMELTS HLLTAAAFGT MKNSENELAE QLIEQTGDNT LTLMDKGYYS LGLLNGWSLA GEHRHWMIPL RKGAQYEELR KLGKGDHLVK LKTSPQARKK WPGLGNEVTA RLLTVTRKGK VCHLLTSMTD AMRFPGGEMA DLYSHRWEIE LGYREIKQTM QLSRLTLRSK KPELVEQELW GVLLAYNLVR YQMIKMAEHL KGYWPNQLSF SESCGMVMRM LMTLQGASPG RIPELMSDLA SMGQLVKLPT RRGRAFPRVV KERPWKYPTA PKKSQSVA //