ID D1LUZ4_HUMAN Unreviewed; 110 AA. AC D1LUZ4; DT 19-JAN-2010, integrated into UniProtKB/TrEMBL. DT 19-JAN-2010, sequence version 1. DT 02-MAR-2010, entry version 3. DE SubName: Full=RUNX1/CBFA2T2 fusion protein type 2; DE Flags: Fragment; GN Name=RUNX1/CBFA2T2 fusion; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Bone marrow/blood; RA Guastadisegni M.C., Lonoce A., Impera L., Fugazza G., Aliano S., RA Grasso R., Raynaud S., Rocchi M., Storlazzi C.T.; RT "Two novel fusions involving RUNX1 in acute myeloid leukemia with a RT t(20;21) translocation: CBFA2T2 and C20orf112."; RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GU070939; ACY95287.1; -; mRNA. DR GO; GO:0005634; C:nucleus; IEA:InterPro. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0003700; F:transcription factor activity; IEA:InterPro. DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. DR InterPro; IPR013524; AML1/Runt_N. DR InterPro; IPR000040; AML1_Runt. DR InterPro; IPR008967; p53-like_TF_DNA-bd. DR InterPro; IPR012346; p53/RUNT-type_TF_DNA_bd. DR Gene3D; G3DSA:2.60.40.720; p53_RUNT_DNA_bd; 1. DR PANTHER; PTHR11950; AML1_Runt; 1. DR Pfam; PF00853; Runt; 1. DR SUPFAM; SSF49417; P53_like_DNA_bnd; 1. DR PROSITE; PS51062; RUNT; 1. PE 2: Evidence at transcript level; FT NON_TER 1 1 FT NON_TER 110 110 SQ SEQUENCE 110 AA; 12353 MW; 77E5773123372D7C CRC64; FTLTITVFTN PPQVATYHRA IKITVDGPRE PRRHRQKLDD QTKPGSLSFS ERLSELEQLR RTAMRVSPHH PAPTPNPRAS LNHSTAFNPQ PQSQMQVGPE KRVPAMPGSP //