ID   D0Z677_9TELE            Unreviewed;       516 AA.
AC   D0Z677;
DT   19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2010, sequence version 1.
DT   11-JUN-2014, entry version 25.
DE   RecName: Full=Cytochrome c oxidase subunit 1;
DE            EC=1.9.3.1;
GN   Name=COI;
OS   Bathytroctes breviceps.
OG   Mitochondrion.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Alepocephali;
OC   Alepocephaliformes; Alepocephalidae; Bathytroctes.
OX   NCBI_TaxID=492029;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RA   Poulsen J.Y., Moller P.R., Lavoue S., Knudsen S.W., Nishida M.,
RA   Miya M.;
RT   "Higher and lower-level relationships of the deep-sea fish order
RT   Alepocephaliformes (Teleostei: Otocephala) inferred from whole
RT   mitogenome sequences.";
RL   Biol. J. Linn. Soc. Lond. 98:923-936(2009).
CC   -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
CC       chain that catalyzes the reduction of oxygen to water. Subunits 1-
CC       3 form the functional core of the enzyme complex. CO I is the
CC       catalytic subunit of the enzyme. Electrons originating in
CC       cytochrome c are transferred via the copper A center of subunit 2
CC       and heme A of subunit 1 to the bimetallic center formed by heme A3
CC       and copper B (By similarity).
CC   -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
CC       ferricytochrome c + 2 H(2)O.
CC   -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass
CC       membrane protein (By similarity).
CC   -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP009576; BAI50171.1; -; Genomic_DNA.
DR   RefSeq; YP_003331265.1; NC_013574.1.
DR   GeneID; 8656288; -.
DR   CTD; 4512; -.
DR   UniPathway; UPA00705; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
DR   GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.20.210.10; -; 1.
DR   InterPro; IPR000883; Cyt_c_Oxase_su1.
DR   InterPro; IPR023615; Cyt_c_Oxase_su1_BS.
DR   InterPro; IPR023616; Cyt_c_Oxase_su1_dom.
DR   PANTHER; PTHR10422; PTHR10422; 1.
DR   Pfam; PF00115; COX1; 1.
DR   PRINTS; PR01165; CYCOXIDASEI.
DR   SUPFAM; SSF81442; SSF81442; 1.
DR   PROSITE; PS50855; COX1; 1.
DR   PROSITE; PS00077; COX1_CUB; 1.
PE   3: Inferred from homology;
KW   Copper; Electron transport; Heme; Iron; Membrane; Metal-binding;
KW   Mitochondrion; Mitochondrion inner membrane; Oxidoreductase;
KW   Respiratory chain; Transmembrane; Transport.
SQ   SEQUENCE   516 AA;  56837 MW;  1D7709962E9204FE CRC64;
     MAITRWFFST NHKDIGTLYL VFGAWAGMVG TALSLLIRAE LSQPGALLGD DQIYNVIVTA
     HAFVMIFFMV MPIMIGGFGN WLLPLMLGAP DMAFPRMNNM SFWLLPPSLL LLLSSSGVEA
     GVGTGWTVYP PLAGNLAHAG ASVDLAIFSL HLAGVSSILG SINFITTITN MKPPAISQYQ
     TPLFVWSLLV TTVLLLLSLP VLAAAITMLL TDRNLNTTFF DPAGGGDPIL YQHLFWFFGH
     PEVYILILPG FGIVSHVVAY YAGKKEPFGY MGMVWAMMAI GLLGFIVWAH HMFTVGMDVD
     TRAYFTSATM IIAIPTGVKV FSWLATLHGG SIKWETPLLW ALGFIFLFTV GGLTGIVLSN
     SSLDIVLHDT YYVVAHFHYV LSMGAVFAIM AGFVHWFPLF SGYTLHSTWS KIHFGVMFLG
     VNLTFFPQHF LGLAGMPRRY SDYPDAYALW NTVSSIGSMI SMVAVIMFLF ILWEAFAAKR
     EVLSVELTST NVEWLHGCPP PYHTFEEPAF VQVQAN
//