ID D0KMU6_SULS9 Unreviewed; 249 AA. AC D0KMU6; DT 15-DEC-2009, integrated into UniProtKB/TrEMBL. DT 15-DEC-2009, sequence version 1. DT 05-SEP-2012, entry version 13. DE RecName: Full=Probable inorganic polyphosphate/ATP-NAD kinase; DE Short=Poly(P)/ATP NAD kinase; DE EC=2.7.1.23; GN Name=ppnK; OrderedLocusNames=Ssol_0037; OS Sulfolobus solfataricus (strain 98/2). OC Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; OC Sulfolobus. OX NCBI_TaxID=555311; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=98/2; RG US DOE Joint Genome Institute; RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., RA Bruce D., Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., RA Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., RA Ovchinnikova G., Mead D.; RT "Complete sequence of Sulfolobus solfataricus 98/2."; RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Catalyzes the phosphorylation of NAD to NADP. Utilizes CC ATP and other nucleoside triphosphates as well as inorganic CC polyphosphate as a source of phosphorus (By similarity). CC -!- CATALYTIC ACTIVITY: ATP + NAD(+) = ADP + NADP(+). CC -!- COFACTOR: Divalent metal ions (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). CC -!- SIMILARITY: Belongs to the NAD kinase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP001800; ACX90342.1; -; Genomic_DNA. DR RefSeq; YP_005641943.1; NC_017274.1. DR ProteinModelPortal; D0KMU6; -. DR GeneID; 12258063; -. DR GenomeReviews; CP001800_GR; Ssol_0037. DR KEGG; sol:Ssol_0037; -. DR HOGENOM; HOG000270621; -. DR OMA; VDPRLDV; -. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0046872; F:metal ion binding; IEA:HAMAP. DR GO; GO:0003951; F:NAD+ kinase activity; IEA:HAMAP. DR Gene3D; G3DSA:2.60.200.30; ATP-NAD_kinase_PpnK-typ; 1. DR Gene3D; G3DSA:3.40.50.10330; ATP-NAD_kinase_PpnK-typ_a/b; 1. DR HAMAP; MF_00361; NAD_kinase; 1; -. DR InterPro; IPR016064; ATP-NAD_kinase_PpnK-typ. DR InterPro; IPR017438; ATP-NAD_kinase_PpnK-typ_a/b. DR InterPro; IPR017437; ATP-NAD_kinase_PpnK-typ_all-b. DR InterPro; IPR002504; polyP/ATP_NADK_prd. DR PANTHER; PTHR20275; ATP_NADK; 1. DR Pfam; PF01513; NAD_kinase; 1. DR SUPFAM; SSF111331; ATP-NAD_kinase_PpnK-typ; 1. PE 3: Inferred from homology; KW ATP-binding; Complete proteome; Cytoplasm; Kinase; NAD; NADP; KW Nucleotide-binding; Transferase. SQ SEQUENCE 249 AA; 27890 MW; D4AD6A9F7DCD8A49 CRC64; MRVKIVSKPT SQLNYTVEKI KNISNKLGFE VVDIDFDYVI AVGGDGTLLR AVKLGKPVIA IKAGRRGLLM DVPVDKIEDA LLRLKKGDYN EEEYMLLEMV HNDKVELGFN EIGILYDRPE AIKVGISFDT ERVSVEGDGV LVSTPQGSSG WGMSATNSLL YKDLNAIEII FVNPIFYYLR SVVIPPKSLI LRLEDKGYPQ TARVVVDGEV VTLIKTNQEI TVRVSQHKAK ILRFFKLDLI GEVLHAYHI //