ID   D0E983_9HEMI            Unreviewed;       177 AA.
AC   D0E983;
DT   24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   24-NOV-2009, sequence version 1.
DT   11-DEC-2019, entry version 38.
DE   RecName: Full=Cytochrome c oxidase subunit 2 {ECO:0000256|RuleBase:RU000457};
DE   Flags: Fragment;
GN   Name=COII {ECO:0000313|EMBL:ACX48336.1};
OS   Diaspididae sp. D0752A.
OG   Mitochondrion {ECO:0000313|EMBL:ACX48336.1}.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Coccoidea; Diaspididae;
OC   unclassified Diaspididae.
OX   NCBI_TaxID=670958 {ECO:0000313|EMBL:ACX48336.1};
RN   [1] {ECO:0000313|EMBL:ACX48336.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=D0752A {ECO:0000313|EMBL:ACX48336.1};
RX   PubMed=20460159; DOI=10.1016/j.ympev.2010.05.002;
RA   Andersen J.C., Wu J., Gruwell M.E., Gwiazdowski R., Santana S.E.,
RA   Feliciano N.M., Morse G.E., Normark B.B.;
RT   "A phylogenetic analysis of armored scale insects (Hemiptera: Diaspididae),
RT   based upon nuclear, mitochondrial, and endosymbiont gene sequences.";
RL   Mol. Phylogenet. Evol. 57:992-1003(2010).
CC   -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
CC       chain that catalyzes the reduction of oxygen to water. Subunits 1-3
CC       form the functional core of the enzyme complex. Subunit 2 transfers the
CC       electrons from cytochrome c via its binuclear copper A center to the
CC       bimetallic center of the catalytic subunit 1.
CC       {ECO:0000256|RuleBase:RU000457}.
CC   -!- COFACTOR:
CC       Name=Cu cation; Xref=ChEBI:CHEBI:23378;
CC         Evidence={ECO:0000256|RuleBase:RU000457};
CC       Note=Binds a copper A center. {ECO:0000256|RuleBase:RU000457};
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000256|RuleBase:RU000457}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU000457}.
CC   -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 2 family.
CC       {ECO:0000256|RuleBase:RU000457}.
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DR   EMBL; GQ425057; ACX48336.1; -; Genomic_DNA.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR   Gene3D; 1.10.287.90; -; 1.
DR   Gene3D; 2.60.40.420; -; 1.
DR   InterPro; IPR002429; CcO_II-like_C.
DR   InterPro; IPR008972; Cupredoxin.
DR   InterPro; IPR011759; Cyt_c_oxidase_su2_TM_dom.
DR   InterPro; IPR036257; Cyt_c_oxidase_su2_TM_sf.
DR   Pfam; PF00116; COX2; 1.
DR   Pfam; PF02790; COX2_TM; 1.
DR   SUPFAM; SSF49503; SSF49503; 1.
DR   SUPFAM; SSF81464; SSF81464; 1.
DR   PROSITE; PS50857; COX2_CUA; 1.
DR   PROSITE; PS50999; COX2_TM; 1.
PE   3: Inferred from homology;
KW   Copper {ECO:0000256|RuleBase:RU000457};
KW   Electron transport {ECO:0000256|RuleBase:RU000457};
KW   Membrane {ECO:0000256|RuleBase:RU000457, ECO:0000256|SAAS:SAAS00883094,
KW   ECO:0000256|SAM:Phobius}; Metal-binding {ECO:0000256|RuleBase:RU000457};
KW   Mitochondrion {ECO:0000256|RuleBase:RU000457, ECO:0000313|EMBL:ACX48336.1};
KW   Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000457};
KW   Respiratory chain {ECO:0000256|RuleBase:RU000457};
KW   Transmembrane {ECO:0000256|RuleBase:RU000457,
KW   ECO:0000256|SAAS:SAAS00882981, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00883111,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000457}.
FT   TRANSMEM        20..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        62..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..90
FT                   /note="COX2_TM"
FT                   /evidence="ECO:0000259|PROSITE:PS50999"
FT   DOMAIN          91..177
FT                   /note="COX2_CUA"
FT                   /evidence="ECO:0000259|PROSITE:PS50857"
FT   NON_TER         177
FT                   /evidence="ECO:0000313|EMBL:ACX48336.1"
SQ   SEQUENCE   177 AA;  21657 MW;  CD2E59E71E97CBD2 CRC64;
     MTWMNLNFQN PNSMNLFKLI MFNNLLMIII MNIFIIMLMM MKFNMKNKFN NKNMFNNQLM
     EFMWTMLPMM LIMMIMIVSM NILFMNNEAK KNFINIKMMG NQWFWNYEYP NFNKSFNSYL
     MMNKNFNFFM METDNNLIIP FNYQMMMSLS SMDVIHSWTI PSMNIKMDAI PNQLNNF
//