ID C9JYW1_HUMAN Unreviewed; 163 AA. AC C9JYW1; DT 03-NOV-2009, integrated into UniProtKB/TrEMBL. DT 03-NOV-2009, sequence version 1. DT 08-MAY-2019, entry version 64. DE SubName: Full=Unconventional myosin-Ib {ECO:0000313|Ensembl:ENSP00000401324}; DE Flags: Fragment; GN Name=MYO1B {ECO:0000313|Ensembl:ENSP00000401324}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000401324, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000401324, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=15815621; DOI=10.1038/nature03466; RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., RA Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., RA Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., RA Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J., RA Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., RA Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., RA Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., RA Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., RA Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., RA Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., RA Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., RA Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., RA Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., RA Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., RA Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., RA Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., RA Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., RA Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., RA McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., RA Waterston R.H., Wilson R.K.; RT "Generation and annotation of the DNA sequences of human chromosomes 2 RT and 4."; RL Nature 434:724-731(2005). RN [2] {ECO:0000313|Ensembl:ENSP00000401324} RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. RN [3] {ECO:0000213|PubMed:24275569} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014; RA Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., RA Wang L., Ye M., Zou H.; RT "An enzyme assisted RP-RPLC approach for in-depth analysis of human RT liver phosphoproteome."; RL J. Proteomics 96:253-262(2014). CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase CC superfamily. Myosin family. {ECO:0000256|PROSITE- CC ProRule:PRU00782}. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation CC of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC068056; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC092614; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC118061; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC133534; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR jPOST; C9JYW1; -. DR MaxQB; C9JYW1; -. DR PeptideAtlas; C9JYW1; -. DR PRIDE; C9JYW1; -. DR Ensembl; ENST00000418908; ENSP00000401324; ENSG00000128641. DR UCSC; uc061qtt.1; human. DR HGNC; HGNC:7596; MYO1B. DR OpenTargets; ENSG00000128641; -. DR eggNOG; KOG0164; Eukaryota. DR eggNOG; COG5022; LUCA. DR GeneTree; ENSGT00940000155752; -. DR HOGENOM; HOG000173959; -. DR ChiTaRS; MYO1B; human. DR Proteomes; UP000005640; Chromosome 2. DR Bgee; ENSG00000128641; Expressed in 219 organ(s), highest expression level in visceral pleura. DR ExpressionAtlas; C9JYW1; baseline and differential. DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW. DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0003774; F:motor activity; IEA:UniProtKB-UniRule. DR Gene3D; 3.40.850.10; -; 1. DR InterPro; IPR036961; Kinesin_motor_dom_sf. DR InterPro; IPR001609; Myosin_head_motor_dom. DR InterPro; IPR027417; P-loop_NTPase. DR Pfam; PF00063; Myosin_head; 1. DR PRINTS; PR00193; MYOSINHEAVY. DR SMART; SM00242; MYSc; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR PROSITE; PS51456; MYOSIN_MOTOR; 1. PE 1: Evidence at protein level; KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782}; KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00782, KW ECO:0000256|SAAS:SAAS01035717}; KW Complete proteome {ECO:0000313|Proteomes:UP000005640}; KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00782, KW ECO:0000256|SAAS:SAAS01035770}; KW Myosin {ECO:0000256|PROSITE-ProRule:PRU00782, KW ECO:0000256|SAAS:SAAS01033784}; KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00782, KW ECO:0000256|SAAS:SAAS01035733}; KW Proteomics identification {ECO:0000213|EPD:C9JYW1, KW ECO:0000213|MaxQB:C9JYW1, ECO:0000213|PeptideAtlas:C9JYW1}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT DOMAIN 15 163 Myosin motor. {ECO:0000259|PROSITE: FT PS51456}. FT NP_BIND 108 115 ATP. {ECO:0000256|PROSITE-ProRule: FT PRU00782}. FT NON_TER 163 163 {ECO:0000313|Ensembl:ENSP00000401324}. SQ SEQUENCE 163 AA; 18303 MW; D47B07FF6070FCFF CRC64; MAKMEVKTSL LDNMIGVGDM VLLEPLNEET FINNLKKRFD HSEIYTYIGS VVISVNPYRS LPIYSPEKVE EYRNRNFYEL SPHIFALSDE AYRSLRDQDK DQCILITGES GAGKTEASKL VMSYVAAVCG KGAEVNQVKE QLLQSNPVLE AFGNAKTVRN DNS //