ID C9J7Q4_HUMAN Unreviewed; 150 AA. AC C9J7Q4; DT 03-NOV-2009, integrated into UniProtKB/TrEMBL. DT 29-SEP-2021, sequence version 2. DT 24-JAN-2024, entry version 92. DE RecName: Full=Protein ABHD11 {ECO:0000256|ARBA:ARBA00040124}; DE AltName: Full=Alpha/beta hydrolase domain-containing protein 11 {ECO:0000256|ARBA:ARBA00042703}; GN Name=ABHD11 {ECO:0000313|Ensembl:ENSP00000397666.2}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000397666.2, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000397666.2, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=12853948; DOI=10.1038/nature01782; RA Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., RA Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., RA Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., RA Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H., RA Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., RA Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., RA Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., RA Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., RA Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., RA Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., RA Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., RA Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., RA Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., RA Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., RA Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., RA Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., RA Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., RA McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., RA Wilson R.K.; RT "The DNA sequence of human chromosome 7."; RL Nature 424:157-164(2003). RN [2] {ECO:0007829|PubMed:25944712} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=25944712; RA Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M., Ayoub D., RA Lane L., Bairoch A., Van Dorsselaer A., Carapito C.; RT "N-terminome analysis of the human mitochondrial proteome."; RL Proteomics 15:2519-2524(2015). RN [3] {ECO:0000313|Ensembl:ENSP00000397666.2} RP IDENTIFICATION. RG Ensembl; RL Submitted (SEP-2023) to UniProtKB. CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. CC {ECO:0000256|ARBA:ARBA00008645}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC073846; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR AlphaFoldDB; C9J7Q4; -. DR SMR; C9J7Q4; -. DR ESTHER; human-ABHD11; ABHD11-Acetyl_transferase. DR MassIVE; C9J7Q4; -. DR MaxQB; C9J7Q4; -. DR PeptideAtlas; C9J7Q4; -. DR ProteomicsDB; 8943; -. DR Antibodypedia; 14446; 150 antibodies from 24 providers. DR DNASU; 83451; -. DR Ensembl; ENST00000458339.6; ENSP00000397666.2; ENSG00000106077.19. DR UCSC; uc064egz.1; human. DR HGNC; HGNC:16407; ABHD11. DR VEuPathDB; HostDB:ENSG00000106077; -. DR GeneTree; ENSGT00390000015880; -. DR HOGENOM; CLU_1668838_0_0_1; -. DR OrthoDB; 1123232at2759; -. DR BioGRID-ORCS; 83451; 255 hits in 1156 CRISPR screens. DR ChiTaRS; ABHD11; human. DR GenomeRNAi; 83451; -. DR Proteomes; UP000005640; Chromosome 7. DR Bgee; ENSG00000106077; Expressed in mucosa of transverse colon and 200 other cell types or tissues. DR ExpressionAtlas; C9J7Q4; baseline and differential. DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1. DR InterPro; IPR029058; AB_hydrolase. DR InterPro; IPR000073; AB_hydrolase_1. DR PANTHER; PTHR46118; PROTEIN ABHD11; 1. DR PANTHER; PTHR46118:SF4; PROTEIN ABHD11; 1. DR Pfam; PF00561; Abhydrolase_1; 1. DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1. PE 1: Evidence at protein level; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}; KW Proteomics identification {ECO:0007829|EPD:C9J7Q4, KW ECO:0007829|MaxQB:C9J7Q4}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT DOMAIN 58..145 FT /note="AB hydrolase-1" FT /evidence="ECO:0000259|Pfam:PF00561" FT REGION 19..40 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 150 AA; 16094 MW; E547EBA7FF4B6AD5 CRC64; MLRWTRAWRL PREGLGPHGP SFARVPVAPS SSSGGRGGAE PRPLPLSYRL LDGEAALPAV VFLHGLFGSK TNFNSIAKIL AQQTGRRVLT VDARNHGDSP HSPDMSYEIM SQDLQDLLPQ LGLVPCVVVG HSMGGKTAML LALQRSQPPP //