ID C9J7Q4_HUMAN Unreviewed; 150 AA. AC C9J7Q4; DT 03-NOV-2009, integrated into UniProtKB/TrEMBL. DT 29-SEP-2021, sequence version 2. DT 22-FEB-2023, entry version 87. DE SubName: Full=Abhydrolase domain containing 11 {ECO:0000313|Ensembl:ENSP00000397666.2}; GN Name=ABHD11 {ECO:0000313|Ensembl:ENSP00000397666.2}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000397666.2, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000397666.2, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=12853948; DOI=10.1038/nature01782; RA Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., RA Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., RA Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., RA Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H., RA Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., RA Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., RA Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., RA Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., RA Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., RA Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., RA Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., RA Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., RA Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., RA Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., RA Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., RA Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., RA Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., RA McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., RA Wilson R.K.; RT "The DNA sequence of human chromosome 7."; RL Nature 424:157-164(2003). RN [2] {ECO:0007829|PubMed:25944712} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=25944712; RA Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M., Ayoub D., RA Lane L., Bairoch A., Van Dorsselaer A., Carapito C.; RT "N-terminome analysis of the human mitochondrial proteome."; RL Proteomics 15:2519-2524(2015). RN [3] {ECO:0000313|Ensembl:ENSP00000397666.2} RP IDENTIFICATION. RG Ensembl; RL Submitted (OCT-2022) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC073846; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; NP_001287987.1; NM_001301058.1. DR AlphaFoldDB; C9J7Q4; -. DR SMR; C9J7Q4; -. DR ESTHER; human-ABHD11; ABHD11-Acetyl_transferase. DR MaxQB; C9J7Q4; -. DR PeptideAtlas; C9J7Q4; -. DR ProteomicsDB; 8943; -. DR Antibodypedia; 14446; 136 antibodies from 24 providers. DR DNASU; 83451; -. DR Ensembl; ENST00000458339.6; ENSP00000397666.2; ENSG00000106077.19. DR GeneID; 83451; -. DR UCSC; uc064egz.1; human. DR CTD; 83451; -. DR HGNC; HGNC:16407; ABHD11. DR VEuPathDB; HostDB:ENSG00000106077; -. DR GeneTree; ENSGT00390000015880; -. DR HOGENOM; CLU_1668838_0_0_1; -. DR OrthoDB; 1123232at2759; -. DR BioGRID-ORCS; 83451; 255 hits in 1156 CRISPR screens. DR ChiTaRS; ABHD11; human. DR GenomeRNAi; 83451; -. DR Proteomes; UP000005640; Chromosome 7. DR Bgee; ENSG00000106077; Expressed in mucosa of transverse colon and 198 other tissues. DR ExpressionAtlas; C9J7Q4; baseline and differential. DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1. DR InterPro; IPR029058; AB_hydrolase. DR InterPro; IPR000073; AB_hydrolase_1. DR PANTHER; PTHR46118; PROTEIN ABHD11; 1. DR PANTHER; PTHR46118:SF4; PROTEIN ABHD11; 1. DR Pfam; PF00561; Abhydrolase_1; 1. DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1. PE 1: Evidence at protein level; KW Proteomics identification {ECO:0007829|EPD:C9J7Q4, KW ECO:0007829|MaxQB:C9J7Q4}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT DOMAIN 58..145 FT /note="AB hydrolase-1" FT /evidence="ECO:0000259|Pfam:PF00561" FT REGION 19..40 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 150 AA; 16094 MW; E547EBA7FF4B6AD5 CRC64; MLRWTRAWRL PREGLGPHGP SFARVPVAPS SSSGGRGGAE PRPLPLSYRL LDGEAALPAV VFLHGLFGSK TNFNSIAKIL AQQTGRRVLT VDARNHGDSP HSPDMSYEIM SQDLQDLLPQ LGLVPCVVVG HSMGGKTAML LALQRSQPPP //