ID C8VUY9_DROME Unreviewed; 823 AA. AC C8VUY9; DT 03-NOV-2009, integrated into UniProtKB/TrEMBL. DT 03-NOV-2009, sequence version 1. DT 12-AUG-2020, entry version 58. DE SubName: Full=RH10094p {ECO:0000313|EMBL:ACV53869.1}; GN Name=Pkn-RF {ECO:0000313|EMBL:ACV53869.1}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; OC Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:ACV53869.1}; RN [1] {ECO:0000313|EMBL:ACV53869.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Berkeley {ECO:0000313|EMBL:ACV53869.1}; RA Carlson J., Booth B., Frise E., Park S., Wan K., Yu C., Celniker S.; RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BT099735; ACV53869.1; -; mRNA. DR PeptideAtlas; C8VUY9; -. DR PRIDE; C8VUY9; -. DR HOGENOM; CLU_000288_132_0_1; -. DR SignaLink; C8VUY9; -. DR Bgee; FBgn0020621; Expressed in head and 45 other tissues. DR ExpressionAtlas; C8VUY9; differential. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. DR InterPro; IPR000961; AGC-kinase_C. DR InterPro; IPR011009; Kinase-like_dom_sf. DR InterPro; IPR017892; Pkinase_C. DR InterPro; IPR000719; Prot_kinase_dom. DR InterPro; IPR017441; Protein_kinase_ATP_BS. DR InterPro; IPR008271; Ser/Thr_kinase_AS. DR Pfam; PF00069; Pkinase; 1. DR Pfam; PF00433; Pkinase_C; 1. DR SMART; SM00133; S_TK_X; 1. DR SMART; SM00220; S_TKc; 1. DR SUPFAM; SSF56112; SSF56112; 1. DR PROSITE; PS51285; AGC_KINASE_CTER; 1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. PE 2: Evidence at transcript level; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840}; KW Kinase {ECO:0000256|ARBA:ARBA00022777}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}; KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}. FT DOMAIN 496..755 FT /note="Protein kinase" FT /evidence="ECO:0000259|PROSITE:PS50011" FT DOMAIN 756..823 FT /note="AGC-kinase C-terminal" FT /evidence="ECO:0000259|PROSITE:PS51285" FT REGION 135..278 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 390..420 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 444..465 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 138..170 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 823 AA; 91499 MW; BAB41D8990F3CB16 CRC64; MAVIKLDNIT VGQTSWKQCS QQAWDQRFSI DLDRSRELEI GVYWRDWRSL CAVKVLRLEE FIDDVRHGMA LQLEPQGLLF AEVKFLNPMI SQKPKLRRQR MIFNRQQAKN ISRAKQMNIN VATWGRLLKR NAPNHVHMGS AGSGSSLTGS SPMVVGGSRD SESPISRTPS SDALVEPEPY TPGEQAQNLE FDPDAGINEH VETPGEYPDP AASGLSGMRP LSMHMQGISV LPPESPPVAT GAAGRPNTLS LQMPGASKGQ VIQGGRTAAP TTAPPPPPVL KATSTTPILD QEARISLVHI TLEPINASRT TSCLIEEVAE PDSQPEIKPV AEAQSAKVSE ACVESILPET VEKLETADQV QQVIPQLGKL YVGSSQQQYA QQSSPIIQEP ATPTIYGNSA AAGAPQFPQP AQRQEKQPPQ QQPIYANQYE LNVAKAAAAA SVYSPSSSTT SNSNQQQQQQ RRNVARGLQY RESGGLETGR AGKQPPNAGM LSMDNFRLLS VLGRGHFGKV ILSQLRSNNQ YYAIKALKKG DIIARDEVES LLSEKRIFEV AKAMRHPFLV NLYSCFQTEQ HVCFVMEYAA DGDLMMHIHT DVFLEPRAVF YAACVVLGLQ YLHENKIIYR DLKLDNLLLD TEGYVKIADF GLCKEGMGFG DRTGTFCGTP EFLAPEVLTE TSYTRAVDWW GLGVLIFEML VGESPFPGDD EEEVFDSIVN DEVRYPRFLS LEAIAVMRRL LRKNPERRLG SSERDAEDVK KQAFFRSIVW DDLLLRKVKP PFVPTINHLE DVSNFDEEFT SEKAQLTPPK EPRHLTEEEQ LLFQDFSYTA EWC //