ID C7BBB5_9MUSC Unreviewed; 356 AA. AC C7BBB5; DT 22-SEP-2009, integrated into UniProtKB/TrEMBL. DT 22-SEP-2009, sequence version 1. DT 19-FEB-2014, entry version 12. DE SubName: Full=Desaturase; GN Name=desatF; OS Drosophila trilutea. OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=94114; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=19652700; DOI=10.1371/journal.pbio.1000168; RA Shirangi T.R., Dufour H.D., Williams T.M., Carroll S.B.; RT "Rapid evolution of sex pheromone-producing enzyme expression in RT Drosophila."; RL PLoS Biol. 7:e1000168-e1000168(2009). CC -!- COFACTOR: Iron (By similarity). CC -!- DOMAIN: The histidine box domains may contain the active site CC and/or be involved in metal ion binding (By similarity). CC -!- SIMILARITY: Belongs to the fatty acid desaturase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; FJ869337; ACT76161.1; -; Genomic_DNA. DR GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005506; F:iron ion binding; IEA:InterPro. DR GO; GO:0004768; F:stearoyl-CoA 9-desaturase activity; IEA:InterPro. DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. DR InterPro; IPR005804; Fatty_acid_desaturase-1. DR InterPro; IPR001522; Fatty_acid_desaturase-1_C. DR InterPro; IPR015876; Fatty_acid_desaturase-1_core. DR Pfam; PF00487; FA_desaturase; 1. DR PRINTS; PR00075; FACDDSATRASE. DR PROSITE; PS00476; FATTY_ACID_DESATUR_1; 1. PE 3: Inferred from homology; KW Fatty acid biosynthesis; Fatty acid metabolism; Iron; KW Lipid biosynthesis; Lipid metabolism; Membrane; Oxidoreductase; KW Transmembrane. SQ SEQUENCE 356 AA; 40955 MW; 25876972D05433F4 CRC64; MPPNSRDTAT GVLFESDVET VDGGLTKDVT HLKTTDGSRL QLVWLNIVLF VILHTASLYG VWLLFAEATW TTFLLFIPAV VMTILGVSGG AHRLWAHRTF KANSPLKLIF LFLNTLAFQD AVYYWARDHR VHHKYTETDG DPYNSQRGWF FSHIGWLCCR KHPEVVEKGK QIDLSDLEXD PLVMFQKKYY LLLMPLICFV LPTAVPMYLW GESLNTSXHV MALLRWCLSL NLIWLVNSSA HMFGMKPYDK NISPVDQGFL ITCRVGEGYH NYHHVFPWDY KSAELGKYSQ DVTTKFIDFF AYLGWAYDLK SVSLDLVRRR AERTGDGSHP VWGWGDRDQL MEDIGDTTIS HQRKGK //