ID C5MVT9_9INFA Unreviewed; 274 AA. AC C5MVT9; DT 28-JUL-2009, integrated into UniProtKB/TrEMBL. DT 28-JUL-2009, sequence version 1. DT 08-MAR-2011, entry version 12. DE SubName: Full=Neuraminidase; DE Flags: Fragment; GN Name=NA; OS Influenza A virus (A/Dublin/04/2009(H1N1)). OC Viruses; ssRNA negative-strand viruses; Orthomyxoviridae; OC Influenzavirus A. OX NCBI_TaxID=653735; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=A/Dublin/04/2009; RA Carr M.J., Duffy M., Tuite G., Hall W.W.; RT "Human infection with novel swine-lineage H1N1 influenza virus in RT Ireland."; RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, CC alpha-(2->8)- glycosidic linkages of terminal sialic acid residues CC in oligosaccharides, glycoproteins, glycolipids, colominic acid CC and synthetic substrates. CC -!- SUBUNIT: Homotetramer (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GQ281078; ACS45192.1; -; Viral_cRNA. DR GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-KW. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0019012; C:virion; IEA:UniProtKB-KW. DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro. DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. DR InterPro; IPR001860; Glyco_hydro_34. DR InterPro; IPR011040; Neuraminidase. DR Gene3D; G3DSA:2.120.10.10; Neuraminidase; 1. DR Pfam; PF00064; Neur; 1. DR SUPFAM; SSF50939; Sialidase; 1. PE 3: Inferred from homology; KW Glycosidase; Host cell membrane; Host membrane; Hydrolase; Membrane; KW Transmembrane; Transmembrane helix; Virion. FT NON_TER 1 1 FT NON_TER 274 274 SQ SEQUENCE 274 AA; 30229 MW; AA32410CFA84501C CRC64; NSIRIGSKGD VFVIREPFIS CSPLECRTFF LTQGALLNDK HSNGTIKDRS PYRTLMSCPI GEVPSPYNSR FESVAWSASA CHDGINWLTI GISGPDNGAV AVLKYNGIIT DTIKSWRNNI LRTQESECAC VNGSCFTVMT DGPSDGQASY KIFRIEKGKI VKSVEMNAPN YHYEECSCYP DSSEITCVCR DNWHGSNRPW VSFNQNLEYQ IGYICSGIFG DNPRPNDKTG SCGPVSSNGA NGVKGFSFKY GNGVWIGRTK SISSRNGFEM IWDP //