ID C5MLM0_9INFA Unreviewed; 759 AA. AC C5MLM0; DT 28-JUL-2009, integrated into UniProtKB/TrEMBL. DT 28-JUL-2009, sequence version 1. DT 09-JUL-2014, entry version 20. DE SubName: Full=Polymerase PB2; GN Name=PB2; OS Influenza A virus (A/chicken/East Java/UT6021/2006(H5N1)). OC Viruses; ssRNA negative-strand viruses; Orthomyxoviridae; OC Influenzavirus A. OX NCBI_TaxID=644250; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=A/chicken/East Java/UT6021/2006; RX PubMed=19464724; DOI=10.1016/j.virol.2009.04.024; RA Takano R., Nidom C.A., Kiso M., Muramoto Y., Yamada S., RA Sakai-Tagawa Y., Macken C., Kawaoka Y.; RT "Phylogenetic characterization of H5N1 avian influenza viruses RT isolated in Indonesia from 2003-2007."; RL Virology 390:13-21(2009). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=A/chicken/East Java/UT6021/2006; RA Tankano R.; RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases. CC -!- SUBUNIT: Influenza RNA polymerase is composed of three subunits: CC PB1, PB2 and PA (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GQ122508; ACR49147.1; -; Viral_cRNA. DR GO; GO:0003723; F:RNA binding; IEA:InterPro. DR GO; GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro. DR GO; GO:0006370; P:7-methylguanosine mRNA capping; IEA:UniProtKB-KW. DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro. DR InterPro; IPR001591; RNA_pol_PB2_orthomyxovir. DR Pfam; PF00604; Flu_PB2; 1. DR ProDom; PD001667; RNA_pol_PB2_orthomyxovir; 1. PE 3: Inferred from homology; KW Cap snatching; Eukaryotic host gene expression shutoff by virus; KW Eukaryotic host transcription shutoff by virus; KW Host gene expression shutoff by virus; Host-virus interaction; KW Inhibition of host RNA polymerase II by virus; mRNA capping; KW mRNA processing. SQ SEQUENCE 759 AA; 85821 MW; 1F22DADCD854F33A CRC64; MERIKELRDL MSQSRTREIL TKTTVDHMAI IKKYTSGRQE KNPALRMKWM MAMKYPITAD KRIIEMIPER NEQGQTLWSK TNDAGSDRVM VSPLAVTWWN RNGPTTSAVH YPKVYKTYFE KAERLKHGTF GPVHFRNQVK IRRRVDINPG HADLSAKEAQ DVIMEVVFPN EVGARILTSE SQLTITKEKK EELQDCKIAP LMVAYMLERE LVRKTRFLPV AGGTSSVYIE VLHLTQGTCW EQMYTPGGEV RNDDVDQSLI IAARNIVRRA TVSADPLASL LEMCHSTRIG GTRMVDILRQ NPTEEQAVDI CKAAMGLRIS SSFSFGGFTF KRTSGSSVTK EEEVLTGNLQ TLKIRVHEGY EEFTMVGRRA TAILRKATRR LIQLIVSGRD EQSIAEAIIV AMVFSQEDCM IKAVRGDLNF VNRANQRLNP MHQLLRHFQK DAKVLFQNWG IEPIDNVMGM IGILPDMTPS TEMSLRGVRV SKMGVDEYSS TERVVVSIDR FLRVRDQRGN VLLSPEEVSE TQGTERLTIT YSSSMMWEIN GPESVLVNTY QWIIRNWETV KIQWSQDPTM LYNKMEFEPF QSLVPKAARG QYSGFVRTLF QQMRDVLGTF DTVQIIKLLP FAAAPPEQSR MQFSSLTVNV RGSGMRILVR GNSPVFNYNK ATKRLTVLGK DAGALTEDPD EGTAGVESAV LRGFLILGKE DKRYGPALSI NELSNLAKGE KANVLIGQGD VVLVMKRKRD SSILTDSQTA TKRIRMAIN //