ID C5MLE1_9INFA Unreviewed; 90 AA. AC C5MLE1; DT 28-JUL-2009, integrated into UniProtKB/TrEMBL. DT 28-JUL-2009, sequence version 1. DT 08-NOV-2023, entry version 54. DE RecName: Full=Protein PB1-F2 {ECO:0000256|HAMAP-Rule:MF_04064}; GN Name=PB1-F2 {ECO:0000313|EMBL:ACR49097.1}; GN Synonyms=PB1 {ECO:0000256|HAMAP-Rule:MF_04064}; OS Influenza A virus (A/quail/Yogjakarta/UT1075/2004(H5N1)). OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina; OC Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus; OC Alphainfluenzavirus influenzae; Influenza A virus. OX NCBI_TaxID=644264 {ECO:0000313|EMBL:ACR49097.1, ECO:0000313|Proteomes:UP000113142}; RN [1] {ECO:0000313|EMBL:ACR49097.1, ECO:0000313|Proteomes:UP000113142} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=A/quail/Yogjakarta/UT1075/2004 {ECO:0000313|EMBL:ACR49097.1}; RX PubMed=19464724; DOI=10.1016/j.virol.2009.04.024; RA Takano R., Nidom C.A., Kiso M., Muramoto Y., Yamada S., Sakai-Tagawa Y., RA Macken C., Kawaoka Y.; RT "Phylogenetic characterization of H5N1 avian influenza viruses isolated in RT Indonesia from 2003-2007."; RL Virology 390:13-21(2009). CC -!- FUNCTION: May play an important role in promoting lung pathology in CC both primary viral infection and secondary bacterial infection. CC {ECO:0000256|HAMAP-Rule:MF_04064}. CC -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000256|HAMAP-Rule:MF_04064}. CC Host cytoplasm, host cytosol {ECO:0000256|HAMAP-Rule:MF_04064}. CC -!- SIMILARITY: Belongs to the influenza viruses PB1-F2 family. CC {ECO:0000256|HAMAP-Rule:MF_04064}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GQ122455; ACR49097.1; -; Viral_cRNA. DR SMR; C5MLE1; -. DR Proteomes; UP000113142; Genome. DR GO; GO:0044164; C:host cell cytosol; IEA:UniProtKB-SubCell. DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule. DR HAMAP; MF_04064; INFV_PB1F2; 1. DR InterPro; IPR021045; Flu_proapoptotic_PB1-F2. DR Pfam; PF11986; PB1-F2; 1. PE 3: Inferred from homology; KW Host cytoplasm {ECO:0000256|HAMAP-Rule:MF_04064}; KW Host nucleus {ECO:0000256|HAMAP-Rule:MF_04064}. FT REGION 1..34 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 1..33 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 90 AA; 10845 MW; 0F4E97AED6F01678 CRC64; MEQGQDTPWT QSTEHTNIQK RGSGQQTQRL EHPNSTRLMD HYLRIMSPVG MHKQIVYWKQ WLSLKNPTQG SLKTRVLKRW KLFNKQEWIN //