ID THI4_DESMR Reviewed; 263 AA. AC C4XIR5; DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot. DT 28-JUL-2009, sequence version 1. DT 07-SEP-2016, entry version 49. DE RecName: Full=Putative thiazole biosynthetic enzyme {ECO:0000255|HAMAP-Rule:MF_00304}; GN OrderedLocusNames=DMR_31420; OS Desulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1). OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales; OC Desulfovibrionaceae; Desulfovibrio. OX NCBI_TaxID=573370; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 700980 / DSM 13731 / RS-1; RX PubMed=19675025; DOI=10.1101/gr.088906.108; RA Nakazawa H., Arakaki A., Narita-Yamada S., Yashiro I., Jinno K., RA Aoki N., Tsuruyama A., Okamura Y., Tanikawa S., Fujita N., RA Takeyama H., Matsunaga T.; RT "Whole genome sequence of Desulfovibrio magneticus strain RS-1 RT revealed common gene clusters in magnetotactic bacteria."; RL Genome Res. 19:1801-1808(2009). CC -!- FUNCTION: Involved in biosynthesis of the thiamine precursor CC thiazole. {ECO:0000255|HAMAP-Rule:MF_00304}. CC -!- SIMILARITY: Belongs to the THI4 family. {ECO:0000255|HAMAP- CC Rule:MF_00304}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AP010904; BAH76633.1; -; Genomic_DNA. DR RefSeq; WP_015861787.1; NC_012796.1. DR ProteinModelPortal; C4XIR5; -. DR STRING; 573370.DMR_31420; -. DR EnsemblBacteria; BAH76633; BAH76633; DMR_31420. DR KEGG; dma:DMR_31420; -. DR PATRIC; 21752523; VBIDesMag26496_3012. DR eggNOG; ENOG4105IQJ; Bacteria. DR eggNOG; COG1635; LUCA. DR HOGENOM; HOG000106048; -. DR KO; K03146; -. DR OMA; RMGPVFG; -. DR OrthoDB; POG091H09WG; -. DR BioCyc; DMAG573370:GHJL-3184-MONOMER; -. DR Proteomes; UP000009071; Chromosome. DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro. DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-HAMAP. DR Gene3D; 3.50.50.60; -; 1. DR HAMAP; MF_00304; Thi4; 1. DR InterPro; IPR023753; FAD/NAD-binding_dom. DR InterPro; IPR002922; Thi4_fam. DR InterPro; IPR022828; Thi4_putative. DR SUPFAM; SSF51905; SSF51905; 1. DR TIGRFAMs; TIGR00292; TIGR00292; 1. PE 3: Inferred from homology; KW Complete proteome; FAD; Flavoprotein; NAD; Thiamine biosynthesis. FT CHAIN 1 263 Putative thiazole biosynthetic enzyme. FT /FTId=PRO_1000205004. FT NP_BIND 27 55 FAD or NAD. {ECO:0000255|HAMAP- FT Rule:MF_00304}. SQ SEQUENCE 263 AA; 27873 MW; ADA793304C972638 CRC64; MSLDERIITQ AILETYFEKF KSSLDLDVAI VGGGPSGMTA ARLLAADGFN VALFERKLSL GGGMWGGGMT FNMIVVQEES VHLLTDVGVP VKRYKDNYFT ADAVAATTTL ASAACLAGAK IFNCMSVEDV MLREENGVKR VTGIVINSSP VEIAGLHVDP VVLGSKYLVE ATGHAVEVLQ TLVRKNDVRL NTPSGGIEGE QSMWADTAEI NTVKNTREIF PGLYVAGMAA NASYGSYRMG PIFGGMLLSG EKVAADIAAK LKG //