ID C3U1R3_MUSMA Unreviewed; 51 AA. AC C3U1R3; DT 16-JUN-2009, integrated into UniProtKB/TrEMBL. DT 16-JUN-2009, sequence version 1. DT 15-JUN-2010, entry version 10. DE RecName: Full=Sperm protamine-P1; GN Name=Prm1; OS Mus macedonicus (Macedonian mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10100; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=19364735; DOI=10.1098/rspb.2009.0257; RA Martin-Coello J., Dopazo H., Arbiza L., Ausio J., Roldan E.R., RA Gomendio M.; RT "Sexual selection drives weak positive selection in protamine genes RT and high promoter divergence, enhancing sperm competitiveness."; RL Proc. R. Soc. B 276:2427-2436(2009). CC -!- FUNCTION: Protamines substitute for histones in the chromatin of CC sperm during the haploid phase of spermatogenesis. They compact CC sperm DNA into a highly condensed, stable and inactive complex (By CC similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the protamine-P1 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; FJ411380; ACP41673.1; -; Genomic_DNA. DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW. DR GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. DR InterPro; IPR000221; Protamine_P1. DR Pfam; PF00260; Protamine_P1; 1. DR PROSITE; PS00048; PROTAMINE_P1; 1. PE 3: Inferred from homology; KW Chromosomal protein; Developmental protein; Differentiation; KW DNA condensation; DNA-binding; Nucleosome core; Nucleus; KW Spermatogenesis. SQ SEQUENCE 51 AA; 6958 MW; B61CD660AD1D7978 CRC64; MARYRCCRSK SRSRCRRRRR RCRRRRRRCC RRRRRRCCRR RRSYTIRCKK Y //