ID C3TVH1_CAPIB Unreviewed; 261 AA. AC C3TVH1; DT 16-JUN-2009, integrated into UniProtKB/TrEMBL. DT 16-JUN-2009, sequence version 1. DT 11-DEC-2019, entry version 34. DE RecName: Full=Cytochrome c oxidase subunit 3 {ECO:0000256|RuleBase:RU003375}; GN Name=COXIII {ECO:0000313|EMBL:ACI24451.1}; OS Capra ibex (Ibex). OG Mitochondrion {ECO:0000313|EMBL:ACI24451.1}. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; OC Caprinae; Capra. OX NCBI_TaxID=72542 {ECO:0000313|EMBL:ACI24451.1}; RN [1] {ECO:0000313|EMBL:ACI24451.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=19294454; DOI=10.1007/s00239-009-9208-7; RA Hassanin A., Ropiquet A., Couloux A., Cruaud C.; RT "Evolution of the mitochondrial genome in mammals living at high altitude: RT new insights from a study of the tribe Caprini (Bovidae, Antilopinae)."; RL J. Mol. Evol. 68:293-310(2009). CC -!- FUNCTION: Subunits I, II and III form the functional core of the enzyme CC complex. {ECO:0000256|RuleBase:RU003375}. CC -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 3 family. CC {ECO:0000256|RuleBase:RU003375, ECO:0000256|SAAS:SAAS00709834}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; FJ207526; ACI24451.1; -; Genomic_DNA. DR RefSeq; YP_007625061.1; NC_020623.1. DR GeneID; 14841607; -. DR CTD; 4514; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW. DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro. DR GO; GO:0019646; P:aerobic electron transport chain; IEA:InterPro. DR CDD; cd01665; Cyt_c_Oxidase_III; 1. DR Gene3D; 1.20.120.80; -; 1. DR InterPro; IPR024791; Cyt_c/ubiquinol_Oxase_su3. DR InterPro; IPR033945; Cyt_c_oxase_su3_dom. DR InterPro; IPR000298; Cyt_c_oxidase-like_su3. DR InterPro; IPR035973; Cyt_c_oxidase_su3-like_sf. DR InterPro; IPR013833; Cyt_c_oxidase_su3_a-hlx. DR PANTHER; PTHR11403; PTHR11403; 1. DR Pfam; PF00510; COX3; 1. DR SUPFAM; SSF81452; SSF81452; 1. DR PROSITE; PS50253; COX3; 1. PE 3: Inferred from homology; KW Membrane {ECO:0000256|SAAS:SAAS00709742, ECO:0000256|SAM:Phobius}; KW Mitochondrion {ECO:0000256|RuleBase:RU003375, ECO:0000313|EMBL:ACI24451.1}; KW Transmembrane {ECO:0000256|RuleBase:RU003375, KW ECO:0000256|SAAS:SAAS00709762, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00709799, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 16..35 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 79..102 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 159..177 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 197..220 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 240..260 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 4..261 FT /note="COX3" FT /evidence="ECO:0000259|PROSITE:PS50253" SQ SEQUENCE 261 AA; 29836 MW; C48E789F0FB1C00B CRC64; MTHQTHAYHM VNPSPWPLTG ALSALLLTSG LIMWFHFNST ALLTLGLTTN MLTMYQWWRD VIRESTFQGH HTPPVQKGLR YGMILFIISE VLFFTGFFWA FYHSSLAPTP ELGGCWPPTG IHPLNPLEVP LLNTSVLLAS GVSITWAHHS LMEGDRSHML QALFITITLG LYFTLLQASE YYEAPFTISD GVYGSTFFVA TGFHGLHVII GSTFLIVCFF RQLKFHFTSN HHFGFEAAAW YWHFVDVVWL FLYVSIYWWG S //