ID RLMN_BACAA Reviewed; 362 AA. AC C3P635; DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot. DT 16-JUN-2009, sequence version 1. DT 01-SEP-2009, entry version 4. DE RecName: Full=Ribosomal RNA large subunit methyltransferase N; DE EC=2.1.1.-; DE AltName: Full=23S rRNA m2A2503 methyltransferase; GN Name=rlmN; OrderedLocusNames=BAA_4026; OS Bacillus anthracis (strain A0248). OC Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus; OC Bacillus cereus group. OX NCBI_TaxID=592021; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Dodson R.J., Munk A.C., Bruce D., Detter C., Tapia R., Sutton G., RA Sims D., Brettin T.; RT "Genome sequence of Bacillus anthracis A0248."; RL Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Specifically methylates the adenine in position 2503 of CC 23S rRNA (By similarity). CC -!- COFACTOR: Binds 1 4Fe-4S cluster. The cluster is coordinated with CC 3 cysteines and an exchangeable S-adenosyl-L-methionine CC (Potential). CC -!- SUBCELLULAR LOCATION: Cytoplasm (Potential). CC -!- SIMILARITY: Belongs to the radical SAM superfamily. RlmN family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP001598; ACQ49308.1; -; Genomic_DNA. DR RefSeq; YP_002868101.1; -. DR GeneID; 7853239; -. DR KEGG; bai:BAA_4026; -. DR HAMAP; MF_01849; -; 1. DR InterPro; IPR004383; CHP00048. DR InterPro; IPR006638; Elp3/MiaB/NifB. DR InterPro; IPR007197; Radical_SAM. DR Pfam; PF04055; Radical_SAM; 1. DR PIRSF; PIRSF006004; CHP00048; 1. DR SMART; SM00729; Elp3; 1. DR TIGRFAMs; TIGR00048; CHP48; 1. PE 3: Inferred from homology; KW 4Fe-4S; Complete proteome; Cytoplasm; Iron; Iron-sulfur; KW Metal-binding; Methyltransferase; rRNA processing; KW S-adenosyl-L-methionine; Transferase. FT CHAIN 1 362 Ribosomal RNA large subunit FT methyltransferase N. FT /FTId=PRO_1000188545. FT METAL 125 125 Iron-sulfur (4Fe-4S-S-AdoMet) FT (Potential). FT METAL 129 129 Iron-sulfur (4Fe-4S-S-AdoMet) FT (Potential). FT METAL 132 132 Iron-sulfur (4Fe-4S-S-AdoMet) FT (Potential). SQ SEQUENCE 362 AA; 41553 MW; 5D1D0D3E937245BD CRC64; METTVRKQKK NLETKKPSIY SLQLHEMQDW LKEQGEPKFR AGQIFDWLYK KRVKNYEDMS NLSKGLREKL SNSFDITTLN TLVKQTSSDG TIKFLFQLYD GYSIETVLMR HEYGNSICVT TQVGCRIGCT FCASTLGGLK RNLEAGEIVA QVVEVQRALD ESEERVSSLV VMGIGEPFDN YDNLMGFLRI INHEKGLHIG ARHMTVSTSG IIPKIYKFAE EDLQINFAIS LHAPNSELRS KLMPINRAYK LPDLMEAIKY YVNRTGRRIT FEYGLFGGEN DQVEHAEELA ALLKGVKCHV NLIPVNYVPE RDYVRTPREQ IFLFEKTLKD RGVNVTIRRE QGHDIDAACG QLRAKERKEE TR //