ID C2NBT0_BACCE Unreviewed; 266 AA. AC C2NBT0; DT 16-JUN-2009, integrated into UniProtKB/TrEMBL. DT 16-JUN-2009, sequence version 1. DT 24-JAN-2024, entry version 74. DE RecName: Full=Energy-coupling factor transporter ATP-binding protein EcfA2 {ECO:0000256|RuleBase:RU365104}; DE EC=7.-.-.- {ECO:0000256|RuleBase:RU365104}; GN ORFNames=bcere0004_1270 {ECO:0000313|EMBL:EEK58558.1}; OS Bacillus cereus BGSC 6E1. OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus; OC Bacillus cereus group. OX NCBI_TaxID=526970 {ECO:0000313|EMBL:EEK58558.1}; RN [1] {ECO:0000313|EMBL:EEK58558.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=BGSC 6E1 {ECO:0000313|EMBL:EEK58558.1}; RX PubMed=22645259; DOI=10.1101/gr.134437.111; RA Zwick M.E., Joseph S.J., Didelot X., Chen P.E., Bishop-Lilly K.A., RA Stewart A.C., Willner K., Nolan N., Lentz S., Thomason M.K., RA Sozhamannan S., Mateczun A.J., Du L., Read T.D.; RT "Genomic characterization of the Bacillus cereus sensu lato species: RT Backdrop to the evolution of Bacillus anthracis."; RL Genome Res. 22:1512-1524(2012). CC -!- FUNCTION: ATP-binding (A) component of a common energy-coupling factor CC (ECF) ABC-transporter complex. {ECO:0000256|RuleBase:RU365104}. CC -!- SUBUNIT: Forms a stable energy-coupling factor (ECF) transporter CC complex composed of 2 membrane-embedded substrate-binding proteins (S CC component), 2 ATP-binding proteins (A component) and 2 transmembrane CC proteins (T component). {ECO:0000256|RuleBase:RU365104}. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004202, CC ECO:0000256|RuleBase:RU365104}; Peripheral membrane protein CC {ECO:0000256|ARBA:ARBA00004202, ECO:0000256|RuleBase:RU365104}. CC Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein CC {ECO:0000256|ARBA:ARBA00004170}. CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Energy-coupling CC factor EcfA family. {ECO:0000256|RuleBase:RU365104}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:EEK58558.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; ACLU01000004; EEK58558.1; -; Genomic_DNA. DR AlphaFoldDB; C2NBT0; -. DR HOGENOM; CLU_000604_1_22_9; -. DR Proteomes; UP000000284; Chromosome. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro. DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProt. DR CDD; cd03225; ABC_cobalt_CbiO_domain1; 1. DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1. DR InterPro; IPR003593; AAA+_ATPase. DR InterPro; IPR003439; ABC_transporter-like_ATP-bd. DR InterPro; IPR017871; ABC_transporter-like_CS. DR InterPro; IPR015856; ABC_transpr_CbiO/EcfA_su. DR InterPro; IPR030946; EcfA2. DR InterPro; IPR027417; P-loop_NTPase. DR NCBIfam; TIGR04521; ECF_ATPase_2; 1. DR PANTHER; PTHR43553:SF27; ENERGY-COUPLING FACTOR TRANSPORTER ATP-BINDING PROTEIN ECFA2; 1. DR PANTHER; PTHR43553; HEAVY METAL TRANSPORTER; 1. DR Pfam; PF00005; ABC_tran; 1. DR SMART; SM00382; AAA; 1. DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1. DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1. DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU365104}; KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, KW ECO:0000256|RuleBase:RU365104}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365104}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, KW ECO:0000256|RuleBase:RU365104}; KW Translocase {ECO:0000256|ARBA:ARBA00022967}; KW Transport {ECO:0000256|RuleBase:RU365104}. FT DOMAIN 1..219 FT /note="ABC transporter" FT /evidence="ECO:0000259|PROSITE:PS50893" SQ SEQUENCE 266 AA; 29258 MW; D4F78B821F080493 CRC64; MSFPSGGYYA IIGHTGSGKS TMIQHLNGLL QPTNGTVQIG EHFISAGKKE KKLKPLRKKV GVVFQFPEHQ LFEETVEKDI CFGPTNFGVS EEAAKQKARE AIELVGLEPE LLARSPFELS GGQMRRVAIA GVLAMEPEVL VLDEPTAGLD PKGQNELMEM FYKLHKEKGL TVILVTHNME DAAKYAEQIV VMHKGTVFLQ GSAEEVFSHA DELEKIGVDL PMSLKYKRAI EEKFGISIPK ATLSLEDLTH EVVQVLRKGG HESCSS //