ID C2NBT0_BACCE Unreviewed; 266 AA. AC C2NBT0; DT 16-JUN-2009, integrated into UniProtKB/TrEMBL. DT 16-JUN-2009, sequence version 1. DT 08-MAY-2019, entry version 57. DE RecName: Full=Energy-coupling factor transporter ATP-binding protein EcfA {ECO:0000256|HAMAP-Rule:MF_01710}; DE Short=ECF transporter A component EcfA {ECO:0000256|HAMAP-Rule:MF_01710}; DE EC=3.6.3.- {ECO:0000256|HAMAP-Rule:MF_01710}; GN Name=ecfA {ECO:0000256|HAMAP-Rule:MF_01710}; GN ORFNames=bcere0004_1270 {ECO:0000313|EMBL:EEK58558.1}; OS Bacillus cereus BGSC 6E1. OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus; OC Bacillus cereus group. OX NCBI_TaxID=526970 {ECO:0000313|EMBL:EEK58558.1, ECO:0000313|Proteomes:UP000000284}; RN [1] {ECO:0000313|EMBL:EEK58558.1, ECO:0000313|Proteomes:UP000000284} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=BGSC 6E1 {ECO:0000313|EMBL:EEK58558.1}; RX PubMed=22645259; DOI=10.1101/gr.134437.111; RA Zwick M.E., Joseph S.J., Didelot X., Chen P.E., Bishop-Lilly K.A., RA Stewart A.C., Willner K., Nolan N., Lentz S., Thomason M.K., RA Sozhamannan S., Mateczun A.J., Du L., Read T.D.; RT "Genomic characterization of the Bacillus cereus sensu lato species: RT Backdrop to the evolution of Bacillus anthracis."; RL Genome Res. 22:1512-1524(2012). CC -!- FUNCTION: ATP-binding (A) component of a common energy-coupling CC factor (ECF) ABC-transporter complex. Unlike classic ABC CC transporters this ECF transporter provides the energy necessary to CC transport a number of different substrates. {ECO:0000256|HAMAP- CC Rule:MF_01710, ECO:0000256|SAAS:SAAS00336457}. CC -!- SUBUNIT: Forms a stable energy-coupling factor (ECF) transporter CC complex composed of 2 membrane-embedded substrate-binding proteins CC (S component), 2 ATP-binding proteins (A component) and 2 CC transmembrane proteins (T component). {ECO:0000256|HAMAP- CC Rule:MF_01710}. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP- CC Rule:MF_01710, ECO:0000256|SAAS:SAAS00336455}; Peripheral membrane CC protein {ECO:0000256|HAMAP-Rule:MF_01710, CC ECO:0000256|SAAS:SAAS00336455}. CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Energy- CC coupling factor EcfA family. {ECO:0000256|HAMAP-Rule:MF_01710, CC ECO:0000256|SAAS:SAAS00534256}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:EEK58558.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; ACLU01000004; EEK58558.1; -; Genomic_DNA. DR EnsemblBacteria; EEK58558; EEK58558; bcere0004_1270. DR Proteomes; UP000000284; Chromosome. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0016887; F:ATPase activity; IEA:InterPro. DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro. DR InterPro; IPR003593; AAA+_ATPase. DR InterPro; IPR003439; ABC_transporter-like. DR InterPro; IPR017871; ABC_transporter_CS. DR InterPro; IPR015856; ABC_transpr_CbiO/EcfA_su. DR InterPro; IPR030946; EcfA2. DR InterPro; IPR027417; P-loop_NTPase. DR Pfam; PF00005; ABC_tran; 1. DR SMART; SM00382; AAA; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR TIGRFAMs; TIGR04521; ECF_ATPase_2; 1. DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1. DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1. DR PROSITE; PS51246; CBIO; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_01710, ECO:0000256|PROSITE- KW ProRule:PRU00434, ECO:0000256|SAAS:SAAS00436461, KW ECO:0000313|EMBL:EEK58558.1}; KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_01710, KW ECO:0000256|SAAS:SAAS00436478}; KW Complete proteome {ECO:0000313|Proteomes:UP000000284}; KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_01710, KW ECO:0000256|SAAS:SAAS00436468}; KW Membrane {ECO:0000256|HAMAP-Rule:MF_01710, KW ECO:0000256|SAAS:SAAS00436517}; KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01710, KW ECO:0000256|PROSITE-ProRule:PRU00434, ECO:0000256|SAAS:SAAS00436457}; KW Transport {ECO:0000256|HAMAP-Rule:MF_01710, KW ECO:0000256|SAAS:SAAS00436501}. FT DOMAIN 1 219 ABC transporter. {ECO:0000259|PROSITE: FT PS50893}. FT DOMAIN 1 201 CBIO. {ECO:0000259|PROSITE:PS51246}. FT NP_BIND 13 20 ATP. {ECO:0000256|PROSITE-ProRule: FT PRU00434}. SQ SEQUENCE 266 AA; 29258 MW; D4F78B821F080493 CRC64; MSFPSGGYYA IIGHTGSGKS TMIQHLNGLL QPTNGTVQIG EHFISAGKKE KKLKPLRKKV GVVFQFPEHQ LFEETVEKDI CFGPTNFGVS EEAAKQKARE AIELVGLEPE LLARSPFELS GGQMRRVAIA GVLAMEPEVL VLDEPTAGLD PKGQNELMEM FYKLHKEKGL TVILVTHNME DAAKYAEQIV VMHKGTVFLQ GSAEEVFSHA DELEKIGVDL PMSLKYKRAI EEKFGISIPK ATLSLEDLTH EVVQVLRKGG HESCSS //