ID C0LY68_9INFA Unreviewed; 716 AA. AC C0LY68; DT 05-MAY-2009, integrated into UniProtKB/TrEMBL. DT 05-MAY-2009, sequence version 1. DT 01-SEP-2009, entry version 5. DE SubName: Full=Polymerase PA; GN Name=PA; OS Influenza A virus (A/chicken/Hunan/1793/2007(H5N1)). OC Viruses; ssRNA negative-strand viruses; Orthomyxoviridae; OC Influenzavirus A. OX NCBI_TaxID=610169; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=A/chicken/Hunan/1793/2007; RA Chen J., Chen Z.; RT "Circulation of multiple genotypes of H5N1 avian influenza viruses in RT central China during 2006-2007."; RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Implicated in endonuclease cleavage of capped RNA CC primers. Displays an elongation factor activity in viral RNA CC synthesis. Dispensable for viral transcription, but not CC replication (By similarity). CC -!- SUBUNIT: Influenza RNA polymerase is composed of three subunits: CC PB1, PB2 and PA (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; FJ784799; ACN39478.1; -; Viral_cRNA. DR GO; GO:0003723; F:RNA binding; IEA:InterPro. DR GO; GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro. DR GO; GO:0006350; P:transcription; IEA:InterPro. DR InterPro; IPR001009; RNA-dir_pol_influenzavirus. DR Pfam; PF00603; Flu_PA; 1. PE 3: Inferred from homology; SQ SEQUENCE 716 AA; 82385 MW; 81D023E9086E7728 CRC64; MEDFVRQCFN PMIVELAEKA MKEYGEDPKI ETNKFAAICT HLEVCFMYSD FHFIDERSES IIVESGDPNA LLKHRFEIIE GRDRTMAWTV VNSICNTTGV EKPKFLPDLY DYKENRFIEI GVTRREVHTY YLEKANKIKS EKTHIHIFSF TGEEMATKAD YTLDEESRAR IKTRLFTIRQ EMASRGLWDS FRQSERGEET IEEKFEITGT MRRLADQSLP PNFSSLENFR AYVDGFEPNG CIEGKLSQMS KEVNAKIEPF LKTTPRPLRL PDGPPCSQRS KFLLMDALKL SIEDPSHEGE GIPLYDAIKC MKTFFGWKEP NIVKPHEKGI NPNYLLAWKQ VMAELQDIEN EEKISKTKNM KKTSQLKWAL GENMAPEKVD FEDCKDISDL RQYGSDEPES RSLASWIQSE FNKACELTDS SWIELDEIGE DVAPIEHIAS MRRNYFTAEV SHCRATEYIM KGVYINTALL NASCAAMDDF QLIPMISKCR TKEGRRKTNL YGFIIKGRSH LRNDTDVVNF VSMEFSLTDP RLEPHKWEKY CVLEIGDMLL RTAVGQVSRP MFLYVRTNGT SKIKMKWGME MRRCLLQSLQ QIESMIEAES SVKEKDMTKE FFENKSETWP IGESPKGVEE GSIGKVCRTL LAKSVFNSLY ASSQLEGFSA ESRKLLLIAQ ALRDDLEPGT FDLGGLYEAI EECLINDPWV LLNASWFNSF LAHALK //