ID B9V3I7_9CAEN Unreviewed; 216 AA. AC B9V3I7; DT 24-MAR-2009, integrated into UniProtKB/TrEMBL. DT 24-MAR-2009, sequence version 1. DT 19-MAR-2014, entry version 22. DE RecName: Full=Cytochrome c oxidase subunit 1; DE EC=1.9.3.1; DE Flags: Fragment; GN Name=cox1; OS Semisulcospira paludiformis. OG Mitochondrion. OC Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Gastropoda; OC Caenogastropoda; Sorbeoconcha; Cerithioidea; Semisulcospiridae; OC Semisulcospira. OX NCBI_TaxID=576959; RN [1] RP NUCLEOTIDE SEQUENCE. RA Du Y.Y., Wu X.P., Ouyang S.; RT "Phylogenetic relationships of Pleuroceridae Gastropoda (Mollusca) RT based on mitochondrial COI gene sequences."; RL Submitted (NOV-2008) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory CC chain that catalyzes the reduction of oxygen to water. Subunits 1- CC 3 form the functional core of the enzyme complex. CO I is the CC catalytic subunit of the enzyme. Electrons originating in CC cytochrome c are transferred via the copper A center of subunit 2 CC and heme A of subunit 1 to the bimetallic center formed by heme A3 CC and copper B (By similarity). CC -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4 CC ferricytochrome c + 2 H(2)O. CC -!- PATHWAY: Energy metabolism; oxidative phosphorylation. CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass CC membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; FJ437222; ACM48518.1; -; Genomic_DNA. DR UniPathway; UPA00705; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC. DR GO; GO:0009055; F:electron carrier activity; IEA:InterPro. DR GO; GO:0020037; F:heme binding; IEA:InterPro. DR GO; GO:0005506; F:iron ion binding; IEA:InterPro. DR GO; GO:0009060; P:aerobic respiration; IEA:InterPro. DR GO; GO:1902600; P:hydrogen ion transmembrane transport; IEA:GOC. DR GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway. DR Gene3D; 1.20.210.10; -; 1. DR InterPro; IPR000883; Cyt_c_Oxase_su1. DR InterPro; IPR023616; Cyt_c_Oxase_su1_dom. DR PANTHER; PTHR10422; PTHR10422; 1. DR Pfam; PF00115; COX1; 1. DR PRINTS; PR01165; CYCOXIDASEI. DR SUPFAM; SSF81442; SSF81442; 1. DR PROSITE; PS50855; COX1; 1. PE 3: Inferred from homology; KW Copper; Electron transport; Heme; Iron; Membrane; Metal-binding; KW Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; KW Respiratory chain; Transmembrane; Transport. FT NON_TER 1 1 FT NON_TER 216 216 SQ SEQUENCE 216 AA; 23375 MW; 83D1A482CDE741D3 CRC64; WSGLVGTALS LLIRAELGQP GALLGDDQLY NVIVTAHAFV MIFFLVMPMM IGGFGNWLVP LMLGAPDMAF PRLNNMSFWL LPPALLLLLS SAAVESGVGT GWTVYPPLSS NLAHAGGSVD LAIFSLHLAG ASSILGAVNF ITTIINMRWR GMQFERLPLF IWSVKITAIL LLLSLPVLAG AITMLLTDRN FNTAFFDPAG GGDPILYQHL FWFFGH //