ID DTD_THENN Reviewed; 149 AA. AC B9KAP7; DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot. DT 24-MAR-2009, sequence version 1. DT 22-SEP-2009, entry version 7. DE RecName: Full=D-tyrosyl-tRNA(Tyr) deacylase; DE EC=3.1.-.-; GN Name=dtd; OrderedLocusNames=CTN_1854; OS Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E). OC Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga. OX NCBI_TaxID=309803; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Lim S.K., Kim J.S., Cha S.H., Park B.C., Lee D.S., Tae H.S., RA Kim S.-J., Kim J.J., Park K.J., Lee S.Y.; RT "The genome sequence of the hyperthermophilic bacterium Thermotoga RT neapolitana."; RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free CC tRNA(Tyr). Could be a defense mechanism against a harmful effect CC of D-tyrosine (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). CC -!- SIMILARITY: Belongs to the DTD family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000916; ACM24030.1; -; Genomic_DNA. DR RefSeq; YP_002535396.1; -. DR GeneID; 7377913; -. DR GenomeReviews; CP000916_GR; CTN_1854. DR KEGG; tna:CTN_1854; -. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:HAMAP. DR GO; GO:0019478; P:D-amino acid catabolic process; IEA:HAMAP. DR HAMAP; MF_00518; -; 1. DR InterPro; IPR003732; DTyrtRNA_deacyls. DR Gene3D; G3DSA:3.50.80.10; DTyrtRNA_deacyls; 1. DR PANTHER; PTHR10472; DTyrtRNA_deacyls; 1. DR Pfam; PF02580; Tyr_Deacylase; 1. DR TIGRFAMs; TIGR00256; DTyrtRNA_deacyls; 1. PE 3: Inferred from homology; KW Complete proteome; Cytoplasm; Hydrolase. FT CHAIN 1 149 D-tyrosyl-tRNA(Tyr) deacylase. FT /FTId=PRO_1000146219. FT ACT_SITE 80 80 Nucleophile (By similarity). SQ SEQUENCE 149 AA; 16589 MW; ED6505109AC134B7 CRC64; MRAVVQRVNE AKVIVDEKVV GAIGKGLLVF VGVGKDDTEK DCEWLAEKVS GLRIFEDEEG KMNLSIMDVG GEVLVVSQFT LYGDCRRGKR PSFTEAAPPE KGKELYEKFV DLLEKKGLKV EKGIFRAHMH VHLVNDGPVT LLLDSSRLF //