ID B8YP89_MOUSE Unreviewed; 106 AA. AC B8YP89; DT 03-MAR-2009, integrated into UniProtKB/TrEMBL. DT 03-MAR-2009, sequence version 1. DT 07-APR-2021, entry version 63. DE SubName: Full=E3 ubiquitin-protein ligase parkin {ECO:0000313|Ensembl:ENSMUSP00000156481}; DE SubName: Full=Truncated parkin variant SV3DEL {ECO:0000313|EMBL:ACL93282.1}; DE EC=6.3.2.19 {ECO:0000313|EMBL:ACL93282.1}; GN Name=Prkn {ECO:0000313|Ensembl:ENSMUSP00000156481, GN ECO:0000313|MGI:MGI:1355296}; GN Synonyms=Park2 {ECO:0000313|EMBL:ACL93282.1}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:ACL93282.1}; RN [1] {ECO:0000313|EMBL:ACL93282.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:ACL93282.1}; RC TISSUE=Retina {ECO:0000313|EMBL:ACL93282.1}; RA Campello L., Esteve-Rudd J., Cuenca N., Martin-Nieto J.; RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSMUSP00000156481, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000156481, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000156481} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000156481}; RG Ensembl; RL Submitted (OCT-2018) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC091254; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC091484; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC091777; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC093450; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC105301; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC105305; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC109610; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC122259; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC154288; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CT009575; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; FJ555556; ACL93282.1; -; mRNA. DR Antibodypedia; 4264; 778 antibodies. DR Ensembl; ENSMUST00000233634; ENSMUSP00000156481; ENSMUSG00000023826. DR MGI; MGI:1355296; Prkn. DR GeneTree; ENSGT00390000011034; -. DR ChiTaRS; Prkn; mouse. DR Proteomes; UP000000589; Chromosome 17. DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW. DR InterPro; IPR000626; Ubiquitin-like_dom. DR InterPro; IPR029071; Ubiquitin-like_domsf. DR Pfam; PF00240; ubiquitin; 1. DR SMART; SM00213; UBQ; 1. DR SUPFAM; SSF54236; SSF54236; 1. DR PROSITE; PS50053; UBIQUITIN_2; 1. PE 2: Evidence at transcript level; KW Ligase {ECO:0000313|EMBL:ACL93282.1}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 1..60 FT /note="Ubiquitin-like" FT /evidence="ECO:0000259|PROSITE:PS50053" FT REGION 59..106 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 59..89 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 106 AA; 11482 MW; DD6C3D34D2C3BDF2 CRC64; MIVFVRFNSS YGFPVEVDSD TSILQLKEVV AKRQGVPADQ LRVIFAGKEL PNHLTVQQLN PPTTAFSSTA KAPATRSSLE SSEFSVAPAN KQPSPWPRAH LAGTMS //