ID   B8YP89_MOUSE            Unreviewed;       106 AA.
AC   B8YP89;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   03-JUL-2019, entry version 51.
DE   SubName: Full=E3 ubiquitin-protein ligase parkin {ECO:0000313|Ensembl:ENSMUSP00000156481};
DE   SubName: Full=Truncated parkin variant SV3DEL {ECO:0000313|EMBL:ACL93282.1};
DE            EC=6.3.2.19 {ECO:0000313|EMBL:ACL93282.1};
GN   Name=Prkn {ECO:0000313|Ensembl:ENSMUSP00000156481,
GN   ECO:0000313|MGI:MGI:1355296};
GN   Synonyms=Park2 {ECO:0000313|EMBL:ACL93282.1};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:ACL93282.1};
RN   [1] {ECO:0000313|EMBL:ACL93282.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C57BL/6J {ECO:0000313|EMBL:ACL93282.1};
RC   TISSUE=Retina {ECO:0000313|EMBL:ACL93282.1};
RA   Campello L., Esteve-Rudd J., Cuenca N., Martin-Nieto J.;
RL   Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000156481, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000156481,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA   She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA   Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA   Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA   Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA   Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of
RT   the mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000156481}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000156481};
RG   Ensembl;
RL   Submitted (OCT-2018) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC091254; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC091484; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC091777; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC093450; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC105301; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC105305; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC109610; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC122259; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC154288; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CT009575; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; FJ555556; ACL93282.1; -; mRNA.
DR   Ensembl; ENSMUST00000233634; ENSMUSP00000156481; ENSMUSG00000023826.
DR   MGI; MGI:1355296; Prkn.
DR   GeneTree; ENSGT00390000011034; -.
DR   Proteomes; UP000000589; Chromosome 17.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR015496; Ubiquilin.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   InterPro; IPR000626; Ubiquitin_dom.
DR   PANTHER; PTHR10677; PTHR10677; 1.
DR   Pfam; PF00240; ubiquitin; 1.
DR   SMART; SM00213; UBQ; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
DR   PROSITE; PS50053; UBIQUITIN_2; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW   Ligase {ECO:0000313|EMBL:ACL93282.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT   DOMAIN        1     60       Ubiquitin-like. {ECO:0000259|PROSITE:
FT                                PS50053}.
FT   REGION       59    106       Disordered. {ECO:0000256|MobiDB-lite:
FT                                B8YP89}.
FT   COMPBIAS     59     89       Polar. {ECO:0000256|MobiDB-lite:B8YP89}.
SQ   SEQUENCE   106 AA;  11482 MW;  DD6C3D34D2C3BDF2 CRC64;
     MIVFVRFNSS YGFPVEVDSD TSILQLKEVV AKRQGVPADQ LRVIFAGKEL PNHLTVQQLN
     PPTTAFSSTA KAPATRSSLE SSEFSVAPAN KQPSPWPRAH LAGTMS
//