ID B8K2Q5_HUMAN Unreviewed; 115 AA. AC B8K2Q5; DT 03-MAR-2009, integrated into UniProtKB/TrEMBL. DT 03-MAR-2009, sequence version 1. DT 11-JUL-2012, entry version 25. DE SubName: Full=Mu opioid receptor splice variant MOR-1H; DE Flags: Fragment; GN Name=OPRM1; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=19077058; DOI=10.1111/j.1471-4159.2008.05833.x; RA Xu J., Xu M., Hurd Y.L., Pasternak G.W., Pan Y.X.; RT "Isolation and characterization of new exon 11-associated N-terminal RT splice variants of the human mu opioid receptor gene."; RL J. Neurochem. 108:962-972(2009). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DQ680044; ABH03503.1; -; mRNA. DR IPI; IPI00976694; -. DR RefSeq; NP_001138751.1; NM_001145279.2. DR RefSeq; NP_001138752.1; NM_001145280.2. DR UniGene; Hs.2353; -. DR ProteinModelPortal; B8K2Q5; -. DR STRING; B8K2Q5; -. DR GeneID; 4988; -. DR KEGG; hsa:4988; -. DR CTD; 4988; -. DR HOVERGEN; HBG079754; -. DR KO; K04215; -. DR NextBio; 19206; -. DR Bgee; B8K2Q5; -. DR GO; GO:0016021; C:integral to membrane; IEA:InterPro. DR GO; GO:0005624; C:membrane fraction; IEA:Compara. DR GO; GO:0004979; F:beta-endorphin receptor activity; IEA:InterPro. DR GO; GO:0007191; P:activation of adenylate cyclase activity by dopamine receptor signaling pathway; IEA:Compara. DR GO; GO:0007193; P:inhibition of adenylate cyclase activity by G-protein signaling pathway; IEA:Compara. DR GO; GO:0007626; P:locomotory behavior; IEA:Compara. DR InterPro; IPR000276; 7TM_GPCR_Rhodpsn. DR InterPro; IPR017452; GPCR_Rhodpsn_supfam. DR InterPro; IPR000105; Mu_opioid_rcpt. DR Pfam; PF00001; 7tm_1; 1. DR PRINTS; PR00237; GPCRRHODOPSN. DR PRINTS; PR00537; MUOPIOIDR. DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1. PE 2: Evidence at transcript level; KW Receptor. FT NON_TER 115 115 SQ SEQUENCE 115 AA; 12071 MW; 6D2E8AE9EF7C1C6C CRC64; MDSSAAPTNA SNCTDALAYS SCSPAPSPGS WVNLSHLDGN LSDPCGPNRT DLGGRDSLCP PTGSPSMITA ITIMALYSIV CVVGLFGNFL VMYVIVRYTK MKTATNIYIF NLALA //