ID B8JK22_DANRE Unreviewed; 697 AA. AC B8JK22; DT 03-MAR-2009, integrated into UniProtKB/TrEMBL. DT 03-MAR-2009, sequence version 1. DT 05-OCT-2016, entry version 53. DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSDARP00000039916}; GN Name=acsl1a {ECO:0000313|Ensembl:ENSDARP00000039916, GN ECO:0000313|ZFIN:ZDB-GENE-050809-115}; GN Synonyms=acsl1 {ECO:0000313|ZFIN:ZDB-GENE-050809-115}; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000039916, ECO:0000313|Proteomes:UP000000437}; RN [1] {ECO:0000313|Ensembl:ENSDARP00000105676} RP IDENTIFICATION. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000105676}; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. RN [2] {ECO:0000313|Ensembl:ENSDARP00000039916, ECO:0000313|Proteomes:UP000000437} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000039916, RC ECO:0000313|Proteomes:UP000000437}; RX PubMed=23594743; DOI=10.1038/nature12111; RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T., RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D., RA Saunders D., Wallis J., Babbage A., Hammond S., RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., RA Stemple D.L.; RT "The zebrafish reference genome sequence and its relationship to the RT human genome."; RL Nature 496:498-503(2013). RN [3] {ECO:0000313|Ensembl:ENSDARP00000039916} RP IDENTIFICATION. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000039916}; RG Ensembl; RL Submitted (AUG-2013) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSDARP00000039916}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BX537280; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; XP_005168406.1; XM_005168349.3. DR UniGene; Dr.48541; -. DR STRING; 7955.ENSDARP00000039916; -. DR PeptideAtlas; B8JK22; -. DR Ensembl; ENSDART00000039917; ENSDARP00000039916; ENSDARG00000030514. DR Ensembl; ENSDART00000125125; ENSDARP00000105676; ENSDARG00000030514. DR GeneID; 555308; -. DR CTD; 555308; -. DR ZFIN; ZDB-GENE-050809-115; acsl1a. DR eggNOG; KOG1256; Eukaryota. DR eggNOG; COG1022; LUCA. DR GeneTree; ENSGT00690000101725; -. DR HOVERGEN; HBG050452; -. DR OMA; CSAFVKA; -. DR OrthoDB; EOG091G03G9; -. DR TreeFam; TF313877; -. DR Reactome; R-DRE-2046105; Linoleic acid (LA) metabolism. DR Reactome; R-DRE-2046106; alpha-linolenic acid (ALA) metabolism. DR Reactome; R-DRE-75876; Synthesis of very long-chain fatty acyl-CoAs. DR Proteomes; UP000000437; Chromosome 1. DR Bgee; ENSDARG00000030514; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0003824; F:catalytic activity; IEA:InterPro. DR GO; GO:0008152; P:metabolic process; IEA:InterPro. DR InterPro; IPR020845; AMP-binding_CS. DR InterPro; IPR000873; AMP-dep_Synth/Lig. DR Pfam; PF00501; AMP-binding; 1. DR PROSITE; PS00455; AMP_BINDING; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000437}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Proteomics identification {ECO:0000213|PeptideAtlas:B8JK22}; KW Reference proteome {ECO:0000313|Proteomes:UP000000437}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 21 45 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 116 561 AMP-binding. {ECO:0000259|Pfam:PF00501}. SQ SEQUENCE 697 AA; 77439 MW; 688EBD2CC4C96816 CRC64; MQAQDLIRHL RMPELDDLRQ YVRSLPTNTL MGMGAFAAIT TYWLATRPKA LKPPCDLTMQ SVEVPGKEYA RRSILMDNDT HMTYYYKDAL TLYEFFLRGL RVSNNGPCLG SRKAGQPYKW LSYKEVADRA EFAGSALLHR GHSQSGDKYI GIFAQNRPEW TISELACYTY SLVAVPLYDT LGTEAISYVI DKASITTIIC DIADKARLIL DCVSGRKHSV TTIVIMESFD SELTAQAQNC GIDIISLKEL EAIGKANHKT PIPPKPEDLA LICFTSGTTG NPKGAMLTHG NVVSNCSAFI KITEVHCMLN QTDIHISYLP LAHMFERVVE GVLLCHGAKI GYFQGDIRLL MDDLKNLKPT IFPVVPRLLN RMFDKIFGQA NTPLKRWLLD FATSRKEAEL KSGVVRKDSM WDKLIFSKVQ ASLGGRVRLM ITGAAPVSPT VLTFLRAALG CQFYEGYGQT ECTAGCTMSL PGDWTAGHVG APLPCNFVKL VDVAEMNYFA ANGEGEVCVK GPNVFQGYLK DPEQTSGAVD KAGWLHTGDI GKWLPNGTLK IIDRKKHIFK LAQGEYIAPE KIENIYIRSD PVAQVFVHGD SLQACLVGVV VPDPDFLPGW AKNRGIEGSF NDLCKSKEVK NAILEDMIQL GKEAGLKSFE QVRDIALHLE MFSVQNGLLT PTLKAKRTEL KSRFREQIDQ LYAKIKM //