ID B8JJH3_MOUSE Unreviewed; 63 AA. AC B8JJH3; DT 03-MAR-2009, integrated into UniProtKB/TrEMBL. DT 03-MAR-2009, sequence version 1. DT 12-SEP-2018, entry version 76. DE SubName: Full=Myosin-6 {ECO:0000313|Ensembl:ENSMUSP00000107083}; DE Flags: Fragment; GN Name=Myh6 {ECO:0000313|Ensembl:ENSMUSP00000107083, GN ECO:0000313|MGI:MGI:97255}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000107083, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000107083, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000107083, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000107083} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000107083}; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CT025533; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR ProteinModelPortal; B8JJH3; -. DR SMR; B8JJH3; -. DR MaxQB; B8JJH3; -. DR PRIDE; B8JJH3; -. DR Ensembl; ENSMUST00000111456; ENSMUSP00000107083; ENSMUSG00000040752. DR MGI; MGI:97255; Myh6. DR eggNOG; KOG0161; Eukaryota. DR eggNOG; COG5022; LUCA. DR GeneTree; ENSGT00760000118919; -. DR ChiTaRS; Myh6; mouse. DR Proteomes; UP000000589; Chromosome 14. DR Bgee; ENSMUSG00000040752; Expressed in 129 organ(s), highest expression level in heart. DR ExpressionAtlas; B8JJH3; baseline and differential. DR GO; GO:0016459; C:myosin complex; IEA:Ensembl. DR GO; GO:0001725; C:stress fiber; IEA:Ensembl. DR GO; GO:0030018; C:Z disc; IEA:Ensembl. DR GO; GO:0051015; F:actin filament binding; IEA:InterPro. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0000146; F:microfilament motor activity; IEA:Ensembl. DR GO; GO:0030048; P:actin filament-based movement; IEA:Ensembl. DR GO; GO:0007512; P:adult heart development; IEA:Ensembl. DR GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl. DR GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl. DR GO; GO:0060048; P:cardiac muscle contraction; IEA:Ensembl. DR GO; GO:0048739; P:cardiac muscle fiber development; IEA:Ensembl. DR GO; GO:0014898; P:cardiac muscle hypertrophy in response to stress; IEA:Ensembl. DR GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl. DR GO; GO:0043462; P:regulation of ATPase activity; IEA:Ensembl. DR GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl. DR GO; GO:0060420; P:regulation of heart growth; IEA:Ensembl. DR GO; GO:0002027; P:regulation of heart rate; IEA:Ensembl. DR GO; GO:0002026; P:regulation of the force of heart contraction; IEA:Ensembl. DR GO; GO:0045214; P:sarcomere organization; IEA:Ensembl. DR GO; GO:0007522; P:visceral muscle development; IEA:Ensembl. DR Gene3D; 2.30.30.360; -; 1. DR InterPro; IPR004009; Myosin_N. DR InterPro; IPR008989; Myosin_S1_N. DR Pfam; PF02736; Myosin_N; 1. DR SUPFAM; SSF50084; SSF50084; 1. DR PROSITE; PS51844; SH3_LIKE; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Proteomics identification {ECO:0000213|MaxQB:B8JJH3}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 32 63 Myosin N-terminal SH3-like. FT {ECO:0000259|PROSITE:PS51844}. FT NON_TER 63 63 {ECO:0000313|Ensembl:ENSMUSP00000107083}. SQ SEQUENCE 63 AA; 7143 MW; B3188484DA2395CB CRC64; MTDAQMADFG AAAQYLRKSE KERLEAQTRP FDIRTECFVP DDKEEYVKAK VVSREGGKVT AET //