ID B7ZC46_MOUSE Unreviewed; 440 AA. AC B7ZC46; DT 03-MAR-2009, integrated into UniProtKB/TrEMBL. DT 03-MAR-2009, sequence version 1. DT 03-JUL-2019, entry version 78. DE SubName: Full=Septin-8 {ECO:0000313|Ensembl:ENSMUSP00000113775}; GN Name=Sept8 {ECO:0000313|Ensembl:ENSMUSP00000113775, GN ECO:0000313|MGI:MGI:894310}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000113775, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000213|PubMed:16452087} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=16452087; DOI=10.1074/mcp.T500041-MCP200; RA Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., RA Burlingame A.L.; RT "Comprehensive identification of phosphorylation sites in postsynaptic RT density preparations."; RL Mol. Cell. Proteomics 5:914-922(2006). RN [2] {ECO:0000213|PubMed:17242355} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=17242355; DOI=10.1073/pnas.0609836104; RA Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.; RT "Large-scale phosphorylation analysis of mouse liver."; RL Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000113775, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000113775, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [4] {ECO:0000213|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and RT expression."; RL Cell 143:1174-1189(2010). RN [5] {ECO:0000313|Ensembl:ENSMUSP00000113775} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000113775}; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- CC like GTPase superfamily. Septin GTPase family. CC {ECO:0000256|RuleBase:RU004560, ECO:0000256|SAAS:SAAS00534725}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL596095; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; XP_011247136.1; XM_011248834.2. DR SMR; B7ZC46; -. DR EPD; B7ZC46; -. DR jPOST; B7ZC46; -. DR MaxQB; B7ZC46; -. DR PeptideAtlas; B7ZC46; -. DR PRIDE; B7ZC46; -. DR Ensembl; ENSMUST00000120878; ENSMUSP00000113775; ENSMUSG00000018398. DR GeneID; 20362; -. DR UCSC; uc007iwi.2; mouse. DR CTD; 20362; -. DR MGI; MGI:894310; Sept8. DR eggNOG; KOG2655; Eukaryota. DR eggNOG; COG5019; LUCA. DR GeneTree; ENSGT00940000156068; -. DR HOGENOM; HOG000233586; -. DR OrthoDB; 845354at2759; -. DR ChiTaRS; Sept8; mouse. DR Proteomes; UP000000589; Chromosome 11. DR Bgee; ENSMUSG00000018398; Expressed in 267 organ(s), highest expression level in visual cortex. DR ExpressionAtlas; B7ZC46; baseline and differential. DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW. DR CDD; cd01850; CDC_Septin; 1. DR InterPro; IPR030379; G_SEPTIN_dom. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR016491; Septin. DR Pfam; PF00735; Septin; 1. DR PIRSF; PIRSF006698; Septin; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR PROSITE; PS51719; G_SEPTIN; 1. PE 1: Evidence at protein level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW GTP-binding {ECO:0000256|RuleBase:RU004560, KW ECO:0000256|SAAS:SAAS00312599}; KW Nucleotide-binding {ECO:0000256|RuleBase:RU004560, KW ECO:0000256|SAAS:SAAS00312613}; KW Proteomics identification {ECO:0000213|EPD:B7ZC46, KW ECO:0000213|MaxQB:B7ZC46, ECO:0000213|PeptideAtlas:B7ZC46}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 41 305 Septin-type G. {ECO:0000259|PROSITE: FT PS51719}. FT REGION 1 23 Disordered. {ECO:0000256|MobiDB-lite: FT B7ZC46}. FT REGION 409 440 Disordered. {ECO:0000256|MobiDB-lite: FT B7ZC46}. FT COILED 321 341 {ECO:0000256|SAM:Coils}. FT COILED 343 399 {ECO:0000256|SAM:Coils}. SQ SEQUENCE 440 AA; 50896 MW; 082D175F4731D2CB CRC64; MAATDLERVS NAEPEPRSLS LGGHVGFDSL PDQLVSKSVT QGFSFNILCV GETGIGKSTL MNTLFNTTFE TEEASHHEEC VRLRPQTYDL QESNVHLKLT IVDAVGFGDQ INKDDRPIVD YIDAQFENYL QEELKIRRSL FDYHDTRIHV CLYFITPTGH SLKSLDLVTM KKLDSKVNII PIIAKADTIS KSELHKFKIK IMGELVSNGV QIYQFPTDDE AVAEINAVMN AHLPFAVVGS TEEVKVGNKL VRARQYPWGV VQVENENHCD FVKLREMLIR VNMEDLREQT HSRHYELYRR CKLEEMGFQD SDGDSQPFSL QETYEAKRKE FLSELQRKEE EMRQMFVNKV KETELELKEK ERELHEKFEH LKRIHQEEKR KVEEKRRELE EETNAFNCRK AAMEALQSQA LHATSQQPLR KDKDKKKAGG WSSIYSVTIP //