ID B7Z012_DROME Unreviewed; 1107 AA. AC B7Z012; DT 03-MAR-2009, integrated into UniProtKB/TrEMBL. DT 03-MAR-2009, sequence version 1. DT 31-JUL-2019, entry version 93. DE SubName: Full=Cappuccino, isoform H {ECO:0000313|EMBL:ACL82993.1}; GN Name=capu {ECO:0000313|EMBL:ACL82993.1, GN ECO:0000313|FlyBase:FBgn0000256}; GN Synonyms=capp {ECO:0000313|EMBL:ACL82993.1}, Capu GN {ECO:0000313|EMBL:ACL82993.1}, CG15420 {ECO:0000313|EMBL:ACL82993.1}, GN Dmel\CG3399 {ECO:0000313|EMBL:ACL82993.1}; GN ORFNames=CG3399 {ECO:0000313|EMBL:ACL82993.1, GN ECO:0000313|FlyBase:FBgn0000256}, Dmel_CG3399 GN {ECO:0000313|EMBL:ACL82993.1}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:ACL82993.1, ECO:0000313|Proteomes:UP000000803}; RN [1] {ECO:0000313|EMBL:ACL82993.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., RA Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., RA Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] {ECO:0000313|EMBL:ACL82993.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] {ECO:0000313|EMBL:ACL82993.1, ECO:0000313|Proteomes:UP000000803} RP GENOME REANNOTATION. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [4] {ECO:0000313|EMBL:ACL82993.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002). RN [5] {ECO:0000313|EMBL:ACL82993.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [6] {ECO:0000313|EMBL:ACL82993.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [7] {ECO:0000313|EMBL:ACL82993.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [8] {ECO:0000313|EMBL:ACL82993.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014134; ACL82993.1; -; Genomic_DNA. DR RefSeq; NP_001137786.1; NM_001144314.2. DR EnsemblMetazoa; FBtr0290080; FBpp0288519; FBgn0000256. DR GeneID; 33611; -. DR CTD; 33611; -. DR FlyBase; FBgn0000256; capu. DR eggNOG; KOG1922; Eukaryota. DR eggNOG; ENOG410XQWC; LUCA. DR GeneTree; ENSGT00940000165811; -. DR OrthoDB; 263102at2759; -. DR ChiTaRS; capu; fly. DR GenomeRNAi; 33611; -. DR Proteomes; UP000000803; Chromosome 2L. DR Bgee; FBgn0000256; Expressed in 41 organ(s), highest expression level in testis. DR ExpressionAtlas; B7Z012; differential. DR Genevisible; B7Z012; DM. DR GO; GO:0005884; C:actin filament; IEA:InterPro. DR GO; GO:0008017; F:microtubule binding; IEA:InterPro. DR GO; GO:0045010; P:actin nucleation; IEA:InterPro. DR Gene3D; 1.20.58.2220; -; 1. DR InterPro; IPR015425; FH2_Formin. DR InterPro; IPR042201; FH2_Formin_sf. DR InterPro; IPR001265; Formin_Cappuccino_subfam. DR Pfam; PF02181; FH2; 1. DR PRINTS; PR00828; FORMIN. DR SMART; SM00498; FH2; 1. DR PROSITE; PS51444; FH2; 1. PE 4: Predicted; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000000803}; KW Reference proteome {ECO:0000313|Proteomes:UP000000803}. FT DOMAIN 633 1080 FH2. {ECO:0000259|PROSITE:PS51444}. FT REGION 50 102 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 156 197 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 496 695 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COILED 782 802 {ECO:0000256|SAM:Coils}. FT COILED 1059 1079 {ECO:0000256|SAM:Coils}. FT COMPBIAS 50 67 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 156 174 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 179 193 Pro-rich. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 502 516 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 530 607 Pro-rich. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 664 680 Polar. {ECO:0000256|SAM:MobiDB-lite}. SQ SEQUENCE 1107 AA; 120742 MW; 3333BFE7FF54BDD0 CRC64; MQTDIVFCKA PAKPPRLRRQ LQTPVESEDH CSLSLGQLCQ LQLQYDNKRH EEESQRILMR EKERVQNTPP LTKQPRKRRI APQPPPKPPP KPRKIRTEKT TNDDHCAFIE QLFFETTEAK PSATVVAGVT GPAGPLGATT SSPSLETQST VIISFKSSQT PVQSQTNSAA SENVEDDTAP LPLPPPPPGF GTPTTPLLSS NVLKKVASFT VEKSSAGNNS SNPPNLCPTS DETTLLATPC SSSLTVATLP PEIAVGAAAG GVAGGAGSRR GSSYVPEKLS FAAYEKFEGQ MLIKWLISTM QSNPKSSSGD ANQELFNTLA LQFCNNLKYV GVLKQISNEH LDCGFSPYEM YQWTHTEQPT TSLPLTPGKL DKVAAWPFSS TPSGIRALES ASLASLGAGG VAGSLATIAT ASTASSDNQK TLQQILKKRL LNCTTLAEVH AVVNELLSSV DEPPRRPSKR CVNLTELLNA SEATVYEYNK TGAEGCVKSF TDAETQTESE DCEGTCKCGQ SSTKVSDNES AKEDGEKPHA VAPPPPPPPP PLHAFVAPPP PPPPPPPPPP PLANYGAPPP PPPPPPGSGS APPPPPPAPI EGGGGIPPPP PPMSASPSKT TISPAPLPDP AEGNWFHRTN TMRKSAVNPP KPMRPLYWTR IVTSAPPAPR PPSVANSTDS TENSGSSPDE PPAANGADAP PTAPPATKEI WTEIEETPLD NIDEFTELFS RQAIAPVSKP KELKVKRAKS IKVLDPERSR NVGIIWRSLH VPSSEIEHAI YHIDTSVVSL EALQHMSNIQ ATEDELQRIK EAAGGDIPLD HPEQFLLDIS LISMASERIS CIVFQAEFEE SVTLLFRKLE TVSQLSQQLI ESEDLKLVFS IILTLGNYMN GGNRQRGQAD GFNLDILGKL KDVKSKESHT TLLHFIVRTY IAQRRKEGVH PLEIRLPIPE PADVERAAQM DFEEVQQQIF DLNKKFLGCK RTTAKVLAAS RPEIMEPFKS KMEEFVEGAD KSMAKLHQSL DECRDLFLET MRFYHFSPKA CTLTLAQCTP DQFFEYWTNF TNDFKDIWKK EITSLLNELM KKSKQAQIES RRNVSTKVEK SGRISLKERM LMRRSKN //