ID B7YZT7_DROME Unreviewed; 1269 AA. AC B7YZT7; DT 03-MAR-2009, integrated into UniProtKB/TrEMBL. DT 03-MAR-2009, sequence version 1. DT 16-OCT-2019, entry version 69. DE SubName: Full=Uncharacterized protein, isoform D {ECO:0000313|EMBL:ACL83075.1}; GN Name=BcDNA:GH05582 {ECO:0000313|EMBL:ACL83075.1}; GN Synonyms=Dmel\CG8740 {ECO:0000313|EMBL:ACL83075.1}; GN ORFNames=CG8740 {ECO:0000313|EMBL:ACL83075.1, GN ECO:0000313|FlyBase:FBgn0027585}, Dmel_CG8740 GN {ECO:0000313|EMBL:ACL83075.1}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:ACL83075.1, ECO:0000313|Proteomes:UP000000803}; RN [1] {ECO:0000313|EMBL:ACL83075.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., RA Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., RA Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] {ECO:0000313|EMBL:ACL83075.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] {ECO:0000313|EMBL:ACL83075.1, ECO:0000313|Proteomes:UP000000803} RP GENOME REANNOTATION. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [4] {ECO:0000313|EMBL:ACL83075.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002). RN [5] {ECO:0000313|EMBL:ACL83075.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [6] {ECO:0000313|EMBL:ACL83075.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [7] {ECO:0000313|EMBL:ACL83075.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [8] {ECO:0000313|EMBL:ACL83075.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE013599; ACL83075.1; -; Genomic_DNA. DR RefSeq; NP_001137621.1; NM_001144149.2. DR STRING; 7227.FBpp0288554; -. DR PaxDb; B7YZT7; -. DR EnsemblMetazoa; FBtr0290115; FBpp0288554; FBgn0027585. DR GeneID; 35866; -. DR KEGG; dme:Dmel_CG8740; -. DR FlyBase; FBgn0027585; CG8740. DR eggNOG; ENOG410J5FS; Eukaryota. DR eggNOG; ENOG410XWTW; LUCA. DR InParanoid; B7YZT7; -. DR OMA; DQQPFHF; -. DR OrthoDB; 240917at2759; -. DR PhylomeDB; B7YZT7; -. DR GenomeRNAi; 35866; -. DR Proteomes; UP000000803; Chromosome 2R. DR Bgee; FBgn0027585; Expressed in 30 organ(s), highest expression level in spermathecum. DR ExpressionAtlas; B7YZT7; baseline and differential. DR Genevisible; B7YZT7; DM. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000000803}; KW Reference proteome {ECO:0000313|Proteomes:UP000000803}. FT REGION 27 300 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 341 412 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 469 493 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 506 640 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 671 690 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 721 1179 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 1192 1269 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 38 54 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 91 107 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 147 187 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 188 202 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 205 237 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 280 295 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 346 361 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 375 406 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 470 493 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 506 522 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 523 583 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 584 602 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 603 640 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 764 797 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 798 849 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 866 902 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 903 929 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 943 972 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 994 1014 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 1015 1057 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 1115 1132 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 1219 1234 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 1235 1249 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. SQ SEQUENCE 1269 AA; 144300 MW; 5F24EF3A02D897D6 CRC64; MHTGATNGGP RVSFNRDVHV KRIGQCMVEE MGTSPGKHPS EYDTQPSSQP SYHQLPKDID PEDIRKEAAL VIAQAGRHHS KAENGDNIPS FRAKQKRQSQ PSDFNSLPTR RRKGKPVARS ASDASTKKPA SKRPSIFGLF SRKSDSNVSQ LDRDPRFEDG GARRLVRSKS DVGSSKLARR AEDKAHQGAT SQSKQQLSPI IEQAQREDFF EKDYFRERER RKSDAVTPRE KNESVRGLNE LLARSRSQAE LDGPILPSGP SGGASISAGI RDRIETLQAK SGENMHSSQQ PAERLPLTKG RTVNGLVKRL SMERFSPQPA ISQPAFSYIR PNEGITYAQL DLGEDQVRRS PMDRDVRTPQ REFAPARPPR ASDVRPSYSP TSNGAPLASR PSHSPSPWQQ LSPRNLSDED EGLGYEPRKV YYEEEFPRRS EPPIVPVIRS VSPSPYLDEL GHRRAQLETR ILTRRFGEGA TLERQADRNR EVGRPTPERE PERFHRPVRQ ELSNEFPPER TQVDSGSTLP RMEKTSRYRH TKYYDDGHGG VKETYVRETQ RDGQVRESRH RERIGERERD YNSADRLEQE PKSLDSQLTD QYRSSPELRS QQTQQREQRE DYWQSSLKRD KLQQRSFDKG DSGIENDFRK ESFNGDLTTR WRKRTVLDDI RACESFLRKE RRDSAQQRQF QRQAVPSRLR REHSYVYRER SIDDGSHFDP HLDKYPVATS TLRRREQHST SHSQSQTPKS EDSSTLKRNK KLGGFEKVKQ LFTGSGGGVS NGGSGRSSGS NVSSGKKEQM SNGNSSTLSR RDKDKEREKE RERERYMVRE EEMRSRYREH HTSAQETSRE PKTIDISLRR RLSTPKASPL LVKRSPADKP PKKHLKPKES APAKVEKTSW FRSLDRRAKS SPKELNVSVN GHSETTSSLK RTKRNTTAAP AKNLRFFGDT DLDSNPPTIS KASSMPRSRP PLGQSKHSQS AYHLDRSPPP PARDYRHSLA GQPEGHNRNG TSRQRASSMQ HLDNGSDEVD FRKRRHYSRS RELHDISESG SEPEPTERHK RSSTAGHRAM SLERTVDGPR GQRIEDRPLL GPPKPARSAE RRGLLNSLGQ ENVGYGRDRY PAESSGTEGE SSLHSQRSVV YLHATTVGDI PQPYNLRRRS MSRDDLRKGK QQAPQHPPPL QPMTRTVSRS VSMLAPWKPK HISEGYEINY SQEQNKRMST LPRKPPPHNG ATSASTLSRT GRKNDSSTPT RRYHMDSLER PPPPRSVLSA SNLRSARAK //