ID B7XJ30_ENTBH Unreviewed; 338 AA. AC B7XJ30; DT 03-MAR-2009, integrated into UniProtKB/TrEMBL. DT 03-MAR-2009, sequence version 1. DT 04-FEB-2015, entry version 35. DE RecName: Full=Methionyl aminopeptidase {ECO:0000256|SAAS:SAAS00103114}; DE EC=3.4.11.18 {ECO:0000256|SAAS:SAAS00103114}; GN ORFNames=EBI_27249 {ECO:0000313|EMBL:EED44036.1}; OS Enterocytozoon bieneusi (strain H348) (Microsporidian parasite). OC Eukaryota; Fungi; Microsporidia; Enterocytozoonidae; Enterocytozoon. OX NCBI_TaxID=481877 {ECO:0000313|EMBL:EED44036.1, ECO:0000313|Proteomes:UP000001742}; RN [1] {ECO:0000313|EMBL:EED44036.1, ECO:0000313|Proteomes:UP000001742} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=H348 {ECO:0000313|EMBL:EED44036.1, RC ECO:0000313|Proteomes:UP000001742}; RX PubMed=18060071; DOI=10.1371/journal.pone.0001277; RA Corradi N., Akiyoshi D.E., Morrison H.G., Feng X., Weiss L.M., RA Tzipori S., Keeling P.J.; RT "Patterns of genome evolution among the microsporidian parasites RT Encephalitozoon cuniculi, Antonospora locustae and Enterocytozoon RT bieneusi."; RL PLoS ONE 2:E1277-E1277(2007). RN [2] {ECO:0000313|EMBL:EED44036.1, ECO:0000313|Proteomes:UP000001742} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=H348 {ECO:0000313|EMBL:EED44036.1, RC ECO:0000313|Proteomes:UP000001742}; RX PubMed=19132089; DOI=10.1371/journal.ppat.1000261; RA Akiyoshi D.E., Morrison H.G., Lei S., Feng X., Zhang Q., Corradi N., RA Mayanja H., Tumwine J.K., Keeling P.J., Weiss L.M., Tzipori S.; RT "Genomic survey of the non-cultivatable opportunistic human pathogen, RT Enterocytozoon bieneusi."; RL PLoS Pathog. 5:E1000261-E1000261(2009). CC -!- CATALYTIC ACTIVITY: Release of N-terminal amino acids, CC preferentially methionine, from peptides and arylamides. CC {ECO:0000256|SAAS:SAAS00103104}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00103115}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:EED44036.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; ABGB01000024; EED44036.1; -; Genomic_DNA. DR RefSeq; XP_002650008.1; XM_002649962.1. DR ProteinModelPortal; B7XJ30; -. DR GeneID; 8641627; -. DR EuPathDB; MicrosporidiaDB:EBI_27249; -. DR InParanoid; B7XJ30; -. DR OrthoDB; EOG7BGHW3; -. DR Proteomes; UP000001742; Unassembled WGS sequence. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro. DR Gene3D; 1.10.10.10; -; 1. DR Gene3D; 3.90.230.10; -; 2. DR InterPro; IPR000994; Pept_M24_structural-domain. DR InterPro; IPR002468; Pept_M24A_MAP2. DR InterPro; IPR018349; Pept_M24A_MAP2_BS. DR InterPro; IPR011991; WHTH_DNA-bd_dom. DR PANTHER; PTHR10804:SF9; PTHR10804:SF9; 1. DR Pfam; PF00557; Peptidase_M24; 1. DR SUPFAM; SSF55920; SSF55920; 2. DR TIGRFAMs; TIGR00501; met_pdase_II; 1. DR PROSITE; PS01202; MAP_2; 1. PE 4: Predicted; KW Aminopeptidase {ECO:0000256|SAAS:SAAS00103116, KW ECO:0000313|EMBL:EED44036.1}; KW Complete proteome {ECO:0000313|Proteomes:UP000001742}; KW Cytoplasm {ECO:0000256|SAAS:SAAS00103101}; KW Hydrolase {ECO:0000256|RuleBase:RU003652, KW ECO:0000256|SAAS:SAAS00103119}; KW Metal-binding {ECO:0000256|SAAS:SAAS00103103}; KW Protease {ECO:0000256|SAAS:SAAS00103105}; KW Reference proteome {ECO:0000313|Proteomes:UP000001742}. SQ SEQUENCE 338 AA; 38121 MW; 8F7642BF024B3E3E CRC64; MILINPVQEK PIEFLDKTLF NTTSDTQLND IMRAAEAHKR IRGNLQKILK PGCSVREIIK YVEDSTRIML HGEKNNGIGF PCGVSLNNVA AHFSLNPWNE DIILTKNDVL KIDFGTHSNG RIVDSAFSVS FDEKYTNLLL ATKEATERGI KVIGIDMAVC EIGKEISEVF KSFEFEENGK MINIKPIWNL NGHSIDQYKI HAGISIPSIN NGDYSRITPG FFAIETFAST GIGEIKDYGE CSHFALASRP TTNKIYDKKN EEILNLIKKE FGTLPFSHQH LLYYTQNAKA AVQLLAARKF IDSYPPLVDI PKSYVAQFEH TLYITEKSKF NISKGDDY //