ID B7XGA6_MOUSE Unreviewed; 524 AA. AC B7XGA6; DT 03-MAR-2009, integrated into UniProtKB/TrEMBL. DT 03-MAR-2009, sequence version 1. DT 16-MAR-2016, entry version 44. DE RecName: Full=Alkaline phosphatase {ECO:0000256|RuleBase:RU003947}; DE EC=3.1.3.1 {ECO:0000256|RuleBase:RU003947}; GN Name=Alpl {ECO:0000313|EMBL:BAH03518.1, ECO:0000313|MGI:MGI:87983}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:BAH03518.1}; RN [1] {ECO:0000313|EMBL:BAH03518.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Balb/c {ECO:0000313|EMBL:BAH03518.1}; RC TISSUE=Liver {ECO:0000313|EMBL:BAH03518.1}; RA Kanda G., Ochiai H., Hayashi Y., Harashima H., Kamiya H.; RT "Alkaline phosphatase from liver of mouse strains Balb/c and KK-Ay."; RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: A phosphate monoester + H(2)O = an alcohol + CC phosphate. {ECO:0000256|RuleBase:RU003947}. CC -!- SIMILARITY: Belongs to the alkaline phosphatase family. CC {ECO:0000256|RuleBase:RU003946}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB473959; BAH03518.1; -; mRNA. DR UniGene; Mm.288186; -. DR ProteinModelPortal; B7XGA6; -. DR STRING; 10090.ENSMUSP00000030551; -. DR PaxDb; B7XGA6; -. DR PRIDE; B7XGA6; -. DR MGI; MGI:87983; Alpl. DR eggNOG; KOG4126; Eukaryota. DR eggNOG; COG1785; LUCA. DR HOVERGEN; HBG007345; -. DR NextBio; 35547240; -. DR GO; GO:0004035; F:alkaline phosphatase activity; IEA:UniProtKB-EC. DR Gene3D; 3.40.720.10; -; 1. DR InterPro; IPR017849; Alkaline_Pase-like_a/b/a. DR InterPro; IPR001952; Alkaline_phosphatase. DR InterPro; IPR018299; Alkaline_phosphatase_AS. DR InterPro; IPR017850; Alkaline_phosphatase_core. DR Pfam; PF00245; Alk_phosphatase; 1. DR PRINTS; PR00113; ALKPHPHTASE. DR SMART; SM00098; alkPPc; 1. DR SUPFAM; SSF53649; SSF53649; 1. DR PROSITE; PS00123; ALKALINE_PHOSPHATASE; 1. PE 2: Evidence at transcript level; KW Hydrolase {ECO:0000256|RuleBase:RU003947}; KW Magnesium {ECO:0000256|RuleBase:RU003947}; KW Signal {ECO:0000256|SAM:SignalP}; KW Zinc {ECO:0000256|RuleBase:RU003947}. FT SIGNAL 1 17 {ECO:0000256|SAM:SignalP}. FT CHAIN 18 524 Alkaline phosphatase. {ECO:0000256|SAM: FT SignalP}. FT /FTId=PRO_5002863669. SQ SEQUENCE 524 AA; 57470 MW; 7821200546ABE07A CRC64; MISPFLVLAI GTCLTNSFVP EKERDPSYWR QQAQETLKNA LKLQKLNTNV AKNVIMFLGD GMGVSTVTAA RILKGQLHHN TGEETRLEMD KFPFVALSKT YNTNAQVPDS AGTATAYLCG VKANEGTVGV SAATERTRCN TTQGNEVTSI LRWAKDAGKS VGIVTTTRVN HATPSAAYAH SADRDWYSDN EMPPEALSQG CKDIAYQLMH NIKDIDVIMG GGRKYMYPKN RTDVEYELDE KARGTRLDGL DLISIWKSFK PRHKHSHYVW NRTELLALDP SRVDYLLGLF EPGDMQYELN RNNLTDPSLS EMVEVALQIL TKNPKGFFLL VEGGRIDHGH HEGKAKQALH EAVEMDQAIG KAGAMTSQKD TLTVVTADHS HVFTFGGYTP RGNSIFGLAP MVSDTDKKPF TAILYGNGPG YKVVDGEREN VSMVDYAHNN YQAQSAVPLR HETHGGEDVA VFAKGPMAHL LHGVHEQNYI PHVMAYASCI GANLDHCAWA GSGSAPSPGA LLLPLAVLSL RTLF //