ID B7TIY3_9COLE Unreviewed; 219 AA. AC B7TIY3; B8Y1F8; DT 10-FEB-2009, integrated into UniProtKB/TrEMBL. DT 24-MAR-2009, sequence version 2. DT 18-MAY-2010, entry version 11. DE RecName: Full=Cytochrome c oxidase subunit 1; DE EC=1.9.3.1; DE Flags: Fragment; GN Name=COI; OS Hatchiana sp. THK-2008. OG Mitochondrion. OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Elateriformia; OC Elateroidea; Cantharidae; Cantharinae; Hatchiana. OX NCBI_TaxID=568066; RN [1] RP NUCLEOTIDE SEQUENCE. RA Kang T.H., Park H.C., Kim J.I.; RT "A review of the genus Hatchiana Fender, 1966 (Coleoptera: RT Cantharidae) from Korea using morphological and molecular data."; RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE. RA Kang T.H., Park H.C., Kim J.I., Kim M.A.; RT "Taxonomic review of the genus Hatchiana fender, 1966 (Coleoptera: RT Cantharidae) in Korea based on morphological data and DNA barcode."; RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE. RA Kang T.H., Kim J.I., Kim M.A., Park H.C.; RT "Taxonomic review of the genus Hatchiana Fender, 1966 (Coleoptera: RT Cantharidae) in Korea based on morphological data and DNA barcodes."; RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases. RN [4] RP NUCLEOTIDE SEQUENCE. RC STRAIN=HASPAA, HASPAB, and HASPAC; RA Kang T.H., Park H.C., Han T.M., Kim M.A., Lee Y.B.; RT "Taxonomic Review of the Genus Hatchiana Fender 1966 (Coleoptera: RT Cantharidae) in Korea Based on Morphological Data and DNA Barcodes."; RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory CC chain that catalyzes the reduction of oxygen to water. Subunits 1- CC 3 form the functional core of the enzyme complex. CO I is the CC catalytic subunit of the enzyme. Electrons originating in CC cytochrome c are transferred via the copper A center of subunit 2 CC and heme A of subunit 1 to the bimetallic center formed by heme A3 CC and copper B (By similarity). CC -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4 CC ferricytochrome c + 2 H(2)O. CC -!- PATHWAY: Energy metabolism; oxidative phosphorylation. CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass CC membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; FJ232990; ACJ54125.2; -; Genomic_DNA. DR EMBL; FJ462775; ACL79630.2; -; Genomic_DNA. DR EMBL; FJ646621; ACN41867.1; -; Genomic_DNA. DR EMBL; GU323939; ADC36182.1; -; Genomic_DNA. DR EMBL; GU323940; ADC36183.1; -; Genomic_DNA. DR EMBL; GU323941; ADC36184.1; -; Genomic_DNA. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:EC. DR GO; GO:0009055; F:electron carrier activity; IEA:InterPro. DR GO; GO:0020037; F:heme binding; IEA:InterPro. DR GO; GO:0009060; P:aerobic respiration; IEA:InterPro. DR GO; GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. DR GO; GO:0006810; P:transport; IEA:UniProtKB-KW. DR InterPro; IPR000883; Cyt_c_oxidase_su1. DR Pfam; PF00115; COX1; 1. DR PRINTS; PR01165; CYCOXIDASEI. DR SUPFAM; SSF81442; COX1; 1. DR PROSITE; PS50855; COX1; 1. PE 3: Inferred from homology; KW Copper; Electron transport; Heme; Iron; Membrane; Metal-binding; KW Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; KW Respiratory chain; Transmembrane; Transport. FT NON_TER 1 1 FT NON_TER 219 219 SQ SEQUENCE 219 AA; 23718 MW; 10D9D2D3CB4D4482 CRC64; TLYFIFGAWS GSLGLALSLL IRAELGTPGT LIGNDQLYNV IVTAHAFIMI FFMVMPIMIG GFGNWLVPLM LGAPDMAFPR MNNMSFWFLP PSLMFLLMSS MVESGAGTGW TVYPPLSANI AHSGPSVDLA IFSLHMAGIS SILGAVNFIS TIMNMKPPSM KFDQMPLFVW SVGITALLLL LSLPVLAGAI TMLLSDRNLN TSFFDPMGGG DPILYQHLF //