ID   PS1_ARATH               Reviewed;        1477 AA.
AC   B7SY83; Q9C8N3;
DT   29-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   17-FEB-2016, entry version 59.
DE   RecName: Full=FHA domain-containing protein PS1 {ECO:0000305};
DE   AltName: Full=Protein PARALLEL SPINDLE 1 {ECO:0000303|PubMed:19043546};
DE            Short=AtPS1 {ECO:0000303|PubMed:19043546};
GN   Name=PS1 {ECO:0000303|PubMed:19043546};
GN   OrderedLocusNames=At1g34355 {ECO:0000312|TAIR:AT1G34355};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND DISRUPTION PHENOTYPE.
RX   PubMed=19043546; DOI=10.1371/journal.pgen.1000274;
RA   d'Erfurth I., Jolivet S., Froger N., Catrice O., Novatchkova M.,
RA   Simon M., Jenczewski E., Mercier R.;
RT   "Mutations in AtPS1 (Arabidopsis thaliana parallel spindle 1) lead to
RT   the production of diploid pollen grains.";
RL   PLoS Genet. 4:E1000274-E1000274(2008).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S.,
RA   White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y.,
RA   Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W.,
RA   Chung M.K., Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K.,
RA   Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y.,
RA   Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L.,
RA   Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E.,
RA   Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B.,
RA   Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P.,
RA   Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A.,
RA   Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I.,
RA   Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D.,
RA   Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M.,
RA   Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M.,
RA   Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 408:816-820(2000).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RG   The Arabidopsis Information Resource (TAIR);
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for normal spindle orientation at male meiosis
CC       II and normal formation of tetrad of microspores. Not involved in
CC       female meiosis. {ECO:0000269|PubMed:19043546}.
CC   -!- DISRUPTION PHENOTYPE: Diploid pollen grains (dyads of spores
CC       instead of tetrads) due to defective meiosis II. Abnormal spindle
CC       orientation at meiosis II. {ECO:0000269|PubMed:19043546}.
CC   -!- MISCELLANEOUS: Diploid male spores in sp1 mutants give rise to
CC       viable diploid pollen grains and spontaneous triploid plants in
CC       the next generation. {ECO:0000269|PubMed:19043546}.
CC   -!- SIMILARITY: Contains 1 FHA domain. {ECO:0000255|PROSITE-
CC       ProRule:PRU00086}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG51901.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; EU839993; ACJ23185.1; -; mRNA.
DR   EMBL; AC023913; AAG51901.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE31701.1; -; Genomic_DNA.
DR   PIR; G86467; G86467.
DR   RefSeq; NP_564445.1; NM_103158.2.
DR   UniGene; At.39754; -.
DR   ProteinModelPortal; B7SY83; -.
DR   SMR; B7SY83; 67-141.
DR   STRING; 3702.AT1G34355.1; -.
DR   iPTMnet; B7SY83; -.
DR   PaxDb; B7SY83; -.
DR   EnsemblPlants; AT1G34355.1; AT1G34355.1; AT1G34355.
DR   GeneID; 840337; -.
DR   Gramene; AT1G34355.1; AT1G34355.1; AT1G34355.
DR   KEGG; ath:AT1G34355; -.
DR   TAIR; AT1G34355; -.
DR   eggNOG; ENOG410ITU3; Eukaryota.
DR   eggNOG; ENOG4111R97; LUCA.
DR   OMA; PLVMENL; -.
DR   PRO; PR:B7SY83; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   Genevisible; B7SY83; AT.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0009555; P:pollen development; IMP:TAIR.
DR   Gene3D; 2.60.200.20; -; 1.
DR   Gene3D; 3.40.50.1010; -; 2.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR002716; PIN_dom.
DR   InterPro; IPR029060; PIN_domain-like.
DR   InterPro; IPR008984; SMAD_FHA_domain.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF13638; PIN_4; 1.
DR   SMART; SM00240; FHA; 1.
DR   SMART; SM00670; PINc; 1.
DR   SUPFAM; SSF49879; SSF49879; 1.
DR   SUPFAM; SSF88723; SSF88723; 2.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome; Meiosis; Reference proteome.
FT   CHAIN         1   1477       FHA domain-containing protein PS1.
FT                                /FTId=PRO_0000433007.
FT   DOMAIN       64    115       FHA. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00086}.
SQ   SEQUENCE   1477 AA;  163229 MW;  DE16790E1D60B46A CRC64;
     MEVKEEKLME EKQRLPEKTI PVFTVLKNGA ILKNIFVVNS RDFSSPERNG STVSDDDGEV
     EEILVVGRHP DCDILLTHPS ISRFHLEIRS ISSRQKLFVT DLSSVHGTWV RDLRIEPHGC
     VEVEEGDTIR IGGSTRIYRL HWIPLSRAYD LDNPFVSPLD ASTVLEQEEE NRMLEAENLE
     VAQHQSLENT TSGDEGVLHL DVTSEGTGSS VPSEDEDTYV TTREMSMPVA SPSVLTLVRD
     SVETQKLQFN EDLQTSPKWD LDVIESVAEK LSGSFVRSTQ QSGGDVEGLG CSELFDAAEA
     DECDVRGDGG LHLNVISEKM ESSVPNMIEA ENLEVAQHQS LANTALGDDE DLHLDVTSEG
     TGSSVPSEDE DTYITTMEIS VPLASPNVLT LARDSIKTQK LQSTQDFQTP TMWDLDVVEA
     AAEKPSSSCV LGKKLSGGYV EELGCFELFV AAEADKCDVR GDGSLHLNEI SERMESSMSN
     KEDDPFLAAK ETSSLPLSTD FINPETLWLV EDVQASPEFC TSSVKANAEN PSSGCSPSTE
     QIDGCFETSG CSAFDLAAEV ESLSLHQEVS EETEFVTKEV MGVSSEPLGK ADIRSHEENG
     ESEDSRQVIE VSAEPVAKAD IQSHEENGET EGSRQVIEVS PKSFSEAEPT IEILTGEAQG
     IIGSEFPSEL AVETESENLL HQKSIGETKN EIRSHEDYGE TEDYGETECS WPDIAVSPSS
     VSPPEPTLEI LTDEARGLLG SEFLSEVTVE TEIENLLHQK SNVETKADIL IHEDYGETEV
     SRQIITVSPN SFSKAEPTLE TEDSRQQARG LVGSDSEFQS EVAMKTECEN LLNQKRNGET
     KVSSRQASPV SDCLSTPKDR LSSINTDDIQ SLCSSSQPPS ESEVNPATDQ DQESGIISET
     EKPKTELLIG SGRSEKYYSL SEIEGEENTD IGRLSRCPIP SALAAKTSED TKLIEELSSS
     DSGSQENQTP ETHAVRDDVL CDMDSSSTCN IWSRRGKAAS VLKIRTNKSQ GKQKQTGRQP
     KDKLHRKQAL SDKSISLTIH HGAEILEPEI FTPDKENLTP SSHMLKRLQD IGDVKDSKSS
     LKLSGKSCSS LVHSSIAVLA SEAFTEPEIF TPDKENLTPS SHMLKRLREF GDIKDTKGSS
     SKATRKPFFD IRMEENVMVE QEPEDLHSLG SKSKLKHEPL APKKKAERAP FQPLLEKSSF
     QSQSYTEASS TASARNNISR GIRSSSNLSD AKSKMKWTIV LDTSSLLDKE SRKPLQLLQG
     LKGTHLVVPR TVLRELNEVK RSRSFLFRRR TEIASSALDW IEECKVNSKW WIQVQSPTEE
     TKAIAPTPPV TPQSNGSSAF PFSLHWNNYA PEIDSPTSED QVLECALLYR NRNRDEKLVL
     LSNDVTLKIK AMAEGVICET PHEFYESLVN PFSERFMWTE STARGRTWSH LDNDVLRERY
     NDRACRRKST YNRGESGAAA KGLKLILLHN SHYGHTH
//