ID NUSB_ECOLU Reviewed; 139 AA. AC B7N8W8; DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot. DT 24-MAR-2009, sequence version 1. DT 23-FEB-2022, entry version 63. DE RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073}; DE AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073}; GN Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=ECUMN_0454; OS Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC). OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Escherichia. OX NCBI_TaxID=585056; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=UMN026 / ExPEC; RX PubMed=19165319; DOI=10.1371/journal.pgen.1000344; RA Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P., RA Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H., RA Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E., RA Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C., RA Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S., RA Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J., RA Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.; RT "Organised genome dynamics in the Escherichia coli species results in RT highly diverse adaptive paths."; RL PLoS Genet. 5:E1000344-E1000344(2009). CC -!- FUNCTION: Involved in transcription antitermination. Required for CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons. CC {ECO:0000255|HAMAP-Rule:MF_00073}. CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP- CC Rule:MF_00073}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CU928163; CAR11669.1; -; Genomic_DNA. DR RefSeq; WP_000801125.1; NC_011751.1. DR RefSeq; YP_002411217.1; NC_011751.1. DR SMR; B7N8W8; -. DR STRING; 585056.ECUMN_0454; -. DR EnsemblBacteria; CAR11669; CAR11669; ECUMN_0454. DR GeneID; 67416509; -. DR KEGG; eum:ECUMN_0454; -. DR PATRIC; fig|585056.7.peg.657; -. DR HOGENOM; CLU_087843_4_1_6; -. DR OMA; DRMPVVD; -. DR Proteomes; UP000007097; Chromosome. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule. DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro. DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW. DR Gene3D; 1.10.940.10; -; 1. DR HAMAP; MF_00073; NusB; 1. DR InterPro; IPR035926; NusB-like_sf. DR InterPro; IPR011605; NusB_fam. DR InterPro; IPR006027; NusB_RsmB_TIM44. DR PANTHER; PTHR11078; PTHR11078; 1. DR Pfam; PF01029; NusB; 1. DR SUPFAM; SSF48013; SSF48013; 1. DR TIGRFAMs; TIGR01951; nusB; 1. PE 3: Inferred from homology; KW RNA-binding; Transcription; Transcription antitermination; KW Transcription regulation. FT CHAIN 1..139 FT /note="Transcription antitermination protein NusB" FT /id="PRO_1000117052" SQ SEQUENCE 139 AA; 15689 MW; 0BB912103061243B CRC64; MKPAARRRAR ECAVQALYSW QLSQNDIADV EYQFLAEQDV KDVDVLYFRE LLAGVATNTA YLDGLMKPYL SRLLEELGQV EKAVLRIALY ELSKRSDVPY KVAINEAIEL AKSFGAEDSH KFVNGVLDKA APVIRPNKK //