ID   B7FAU7_MOUSE            Unreviewed;       272 AA.
AC   B7FAU7;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   29-SEP-2021, entry version 92.
DE   SubName: Full=ATPase, H+ transporting, lysosomal accessory protein {ECO:0000313|EMBL:CAT00736.1};
DE   SubName: Full=V-type proton ATPase subunit S1 {ECO:0000313|Ensembl:ENSMUSP00000116162};
DE   Flags: Fragment;
GN   Name=Atp6ap1 {ECO:0000313|EMBL:CAT00736.1,
GN   ECO:0000313|Ensembl:ENSMUSP00000116162, ECO:0000313|MGI:MGI:109629};
GN   ORFNames=RP23-436K3.7-009 {ECO:0000313|EMBL:CAT00736.1};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:CAT00736.1};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000116162, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000116162,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|EMBL:CAT00736.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Ellwood M.;
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0007829|PubMed:21183079}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
RN   [4] {ECO:0000313|Ensembl:ENSMUSP00000116162}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000116162};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the vacuolar ATPase subunit S1 family.
CC       {ECO:0000256|ARBA:ARBA00009037}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL807376; CAT00736.1; -; Genomic_DNA.
DR   SMR; B7FAU7; -.
DR   PeptideAtlas; B7FAU7; -.
DR   PRIDE; B7FAU7; -.
DR   ProteomicsDB; 340918; -.
DR   Antibodypedia; 31229; 208 antibodies.
DR   Ensembl; ENSMUST00000147275; ENSMUSP00000116162; ENSMUSG00000019087.
DR   MGI; MGI:109629; Atp6ap1.
DR   VEuPathDB; HostDB:ENSMUSG00000019087; -.
DR   GeneTree; ENSGT00940000156650; -.
DR   HOGENOM; CLU_039408_0_0_1; -.
DR   ChiTaRS; Atp6ap1; mouse.
DR   Proteomes; UP000000589; Chromosome X.
DR   Bgee; ENSMUSG00000019087; Expressed in cerebellum and 325 other tissues.
DR   ExpressionAtlas; B7FAU7; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro.
DR   GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR   InterPro; IPR008388; ATPase_V1-cplx_s1su.
DR   PANTHER; PTHR12471; PTHR12471; 2.
PE   1: Evidence at protein level;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Proteomics identification {ECO:0007829|EPD:B7FAU7,
KW   ECO:0007829|MaxQB:B7FAU7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           33..272
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015087399"
FT   NON_TER         272
FT                   /evidence="ECO:0000313|EMBL:CAT00736.1"
SQ   SEQUENCE   272 AA;  30071 MW;  58918FEF412FDB27 CRC64;
     MMAATVVSRI RTGTGRAPVM WLSLSLVAVA AAVATEQQVP LVLWSSDRNL WAPVADTHEG
     HITSDMQLST YLDPALELGP RNVLLFLQDK LSIEDFTAYG GVFGNKQDSA FSNLENALDL
     APSSLVLPAV DWYAISTLTT YLQEKLGASP LHVARDITMV AGGLGRQLLQ TQVASPAIHP
     PVSYNDTAPR ILFWAQNFSV AYKDEWKDLT SLTFGVENLN LTGSFWNDSF AMLSLTYEPL
     FGATVTFKFI LASRFYPVSA RYWFAMERLE IH
//